87394-56-7 Usage
Description
1-(3-Bromopyridin-2-yl)piperazine is a chemical compound that features a piperazine ring connected to a pyridine ring, with a bromine atom substitution at the 3 position. This structure positions it as a versatile building block in pharmaceutical research and drug development, particularly for synthesizing biologically active compounds. The presence of the bromine atom in the molecule enhances its utility for further functionalization, making it a valuable intermediate for creating a wide range of pharmacologically significant molecules.
Uses
Used in Pharmaceutical Research and Drug Development:
1-(3-Bromopyridin-2-yl)piperazine serves as a key intermediate in the synthesis of various biologically active compounds. Its unique structure allows for the development of new medications with potential applications across different therapeutic areas.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(3-Bromopyridin-2-yl)piperazine is utilized for the design and synthesis of novel therapeutic agents. Its chemical properties make it suitable for creating molecules that can target specific biological pathways, which is crucial for the treatment of various diseases.
Used in Neurological Disorders Treatment:
1-(3-Bromopyridin-2-yl)piperazine is employed in the development of medications aimed at treating neurological disorders. Its structural attributes can be leveraged to create compounds that modulate neurotransmission or affect other neurological processes, potentially leading to effective treatments for conditions such as Parkinson's disease, Alzheimer's disease, or epilepsy.
Used in Cancer Treatment:
This chemical compound also finds application in the realm of oncology, where it is used in the development of anticancer drugs. The ability to modify its structure allows for the creation of molecules that can target cancer cells specifically, leading to potential advancements in cancer therapy.
Overall, 1-(3-Bromopyridin-2-yl)piperazine is a multifaceted chemical entity with broad applications in the pharmaceutical and medicinal chemistry sectors, offering promising avenues for the development of new treatments for a variety of health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 87394-56-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,3,9 and 4 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 87394-56:
(7*8)+(6*7)+(5*3)+(4*9)+(3*4)+(2*5)+(1*6)=177
177 % 10 = 7
So 87394-56-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H12BrN3/c10-8-2-1-3-12-9(8)13-6-4-11-5-7-13/h1-3,11H,4-7H2
87394-56-7Relevant articles and documents
2-[4-(PYRAZOL-4-YLALKYL)PIPERAZIN-1-YL]-3-PHENYL PYRAZINES AND PYRIDINES AND 3-[4-(PYRAZOL-4-YLALKYL)PIPERAZIN-1-YL]-2-PHENYL PYRIDINES AS 5-HT7 RECEPTOR ANTAGONISTS
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Page/Page column 48, (2009/01/20)
The present invention provides selective 5-HT7 receptor antagonist compounds of Formula I and their use in the treatment of migraine, persistent pain, and anxiety: where A and B are each independently C(H)= or N=, provided that at least one of A and B is -N=, n is 1-3, m is 0-3, and R14 are as defined herein.
4-(2-Pyridyl)piperazine-1-carboxamides: Potent vanilloid receptor 1 antagonists
Sun, Qun,Tafesse, Laykea,Islam, Khondaker,Zhou, Xiaoming,Victory, Sam F.,Zhang, Chongwu,Hachicha, Mohamed,Schmid, Lori A.,Patel, Aniket,Rotshteyn, Yakov,Valenzano, Kenneth J.,Kyle, Donald J.
, p. 3611 - 3616 (2007/10/03)
A series of 4-(2-pyridyl)piperazine-1-carboxamide analogues based on the lead compound 1 was synthesized and evaluated for VR1 antagonist activity in capsaicin-induced (CAP) and pH (5.5)-induced (pH) FLIPR assays in a rat VR1-expressing HEK293 cell line. Potent VR1 antagonists were identified through SAR studies. From these studies, 18 was found to be very potent in the in vitro assay [IC50=4.8 nM (pH) and 35 nM (CAP)] and orally available in rat (F%=15.1).
