873946-15-7

Basic information

• Product Name: 1-Piperidinecarboxylic acid, 3-hydroxy-4-[4-[[(trifluoromethyl)sulfonyl]oxy]phenyl]-5-[[tris(1-methylethyl )silyl]oxy]-, phenylmethyl ester, (3R,4R,5S)-
• CAS NO: 873946-15-7
• Molecular Formula: C29H40F3NO7SSi
• Molecular Weight: 631.786
• Mol File: 873946-15-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-Piperidinecarboxylic acid, 3-hydroxy-4-[4-[[(trifluoromethyl)sulfonyl]oxy]phenyl]-5-[[tris(1-methylethyl )silyl]oxy]-, phenylmethyl ester, (3R,4R,5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarboxylic acid, 3-hydroxy-4-[4-[[(trifluoromethyl)sulfonyl]oxy]phenyl]-5-[[tris(1-methylethyl )silyl]oxy]-, phenylmethyl ester, (3R,4R,5S)-(873946-15-7)
• EPA Substance Registry System: 1-Piperidinecarboxylic acid, 3-hydroxy-4-[4-[[(trifluoromethyl)sulfonyl]oxy]phenyl]-5-[[tris(1-methylethyl )silyl]oxy]-, phenylmethyl ester, (3R,4R,5S)-(873946-15-7)

Safety Data

• Hazardous Substances Data: 873946-15-7(Hazardous Substances Data)

Upstream product

• 873945-31-4 (3R,4R,5S)-4-(4-hydroxy-phenyl)-5-triisopropylsilanyloxy-piperidin-3-ol 
• 501-53-1 benzyl chloroformate 
• 873945-27-8 (3R,4R,5S)-3-hydroxy-4-(4-hydroxy-phenyl)-5-triisopropylsilanyl-oxy-piperidine-1-carboxylic acid benzyl ester 
• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 

Downstream Products

• 873946-14-6 benzyl (3R,4R,5S)-3-hydroxy-4-(4-methoxycarbonylphenyl)-5-triisopropylsilanyl-oxypiperidine-1-carboxylate 
• 912346-39-5 benzyl (3R,4R,5S)-3-hydroxy-5-triisopropylsilanyloxy-4-(4-vinylphenyl)-piperidine-1-carboxylate 

Relevant articles and documents

Substituted piperidines as therapeutic compounds

Described are compounds of the general formula (I) and pharmaceutically acceptable salt thereof, in which R2, R3, W,and X have the definitions illustrated in detail in the description, as beta-secretase, cathepsin D, plasmepsin II an

SUBSTITUTED 4-PHENYLPIPERIDINES

The application relates to substituted 4-phenylpiperidines of the general formula and their salts, preferably their pharmaceutically acceptable salts, in which R2, R3, W and X have the meanings explained in the description, a process for their preparation and the use of these compounds as medicines, especially as renin inhibitors.