873948-11-9

Basic information

• Product Name: benzyl (2S)-2-({(1-R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-5-nitro-2-phenyl-3,4-dihydropyridine-1(2h)-carboxylate
• Synonyms: benzyl (2S)-2-({(1-R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-5-nitro-2-phenyl-3,4-dihydropyridine-1(2h)-carboxylate
• CAS NO: 873948-11-9
• Molecular Weight: 608.537
• Mol File: 873948-11-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: benzyl (2S)-2-({(1-R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-5-nitro-2-phenyl-3,4-dihydropyridine-1(2h)-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (2S)-2-({(1-R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-5-nitro-2-phenyl-3,4-dihydropyridine-1(2h)-carboxylate(873948-11-9)
• EPA Substance Registry System: benzyl (2S)-2-({(1-R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-5-nitro-2-phenyl-3,4-dihydropyridine-1(2h)-carboxylate(873948-11-9)

Safety Data

• Hazardous Substances Data: 873948-11-9(Hazardous Substances Data)

Upstream product

• 530441-95-3 (R)-1-(1-(bromomethoxy)ethyl)-3,5-bis(trifluoromethyl)benzene 
• 552293-34-2 benzyl (2S)-2-({(1-R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-2-phenyl-3,4-dihydropyridine-1(2h)-carboxylate 

Downstream Products

• 867045-65-6 C₃₄H₃₄F₆N₂O₇ 
• 867045-66-7 C₃₄H₃₄F₆N₂O₇ 
• 867045-67-8 C₄₇H₅₀F₆N₂O₇ 
• 873947-63-8 benzyl (2S)-2-({(1R)-1-[3,5-bis(tri-fluoro-methyl)-phenyl]ethoxy}-methyl)-5-nitro-2-phenylpiperidine-1-carboxylate 

Relevant articles and documents

Conformation of gem-disubstituted alkylarylpiperidines and their implication in design and synthesis of a conformationally-rigidified NK 1 antagonist

Piperidines are ubiquitous in pharmaceuticals and bioactive natural products. Understanding the structural and functional properties of piperidines plays a key role in drug design and development. This Letter reported studies of conformation of a set of g

BRIDGED RING NK1 ANTAGONISTS

A compound having the general structure shown in Formula (I): or pharmaceutically acceptable salts and/or solvates thereof are useful in treating diseases or conditions mediated by NK1 receptors, for example various physiological disorders, symptoms or di