874812-62-1Relevant articles and documents
Synthesis and biological evaluation of novel hybrids of phenylsulfonyl furoxan and phenstatin derivatives as potent anti-tumor agents
Huang, Xin,Wang, Yu-Shuang,Ma, Duo,Wang, Yuan-Yuan,Bian, Shi-Da,Zhang, Bo,Qiao, Yu,He, Zi-Ran,Lv, Meng,Cai, Guo-Long,Wang, Zi-Xuan,Liu, Xue-Song,Shi, Jing-Bo,Liu, Ming-Ming
, (2022/01/24)
Hybridization of nitric oxide (NO) donors with known anti-cancer agents have been emerged as a strategy to achieve improved therapeutic effect and to overcome chemo-resistance in cancer therapy. In this study, furoxan moiety as an efficient NO donor was i
Enhanced antitumor potential induced by chloroacetate-loaded benzophenones acting as fused tubulin-pyruvate dehydrogenase kinase 1 (PDHK1) ligands
Dubois, Jo?lle,Farce, Amaury,Floquet, Emilie,Ghinet, Alina,Rigo, Beno?t,Thuru, Xavier
, (2020/02/11)
The majority of cancers detected every year are treated with anti-cancer compounds. Unfortunately, many tumors become resistant to antineoplastic drugs. One option is to use cocktails of compounds acting on different targets to try to overcome the resista
Eaton's reagent-mediated domino π-cationic arylations of aromatic carboxylic acids to iasi-red polymethoxylated polycyclic aromatic hydrocarbons: Products with unprecedented biological activities as tubulin polymerization inhibitors
Ghinet, Alina,Gautret, Philippe,Hijfte, Nathalie Van,Lede, Bertrand,Henichart, Jean-Pierre,Bicu, Elena,Darbost, Ulrich,Rigo, Benoit,Daich, Adam
supporting information, p. 10117 - 10130 (2014/08/18)
A rapid domino π-cationic arylation of aromatic carboxylic acids, mediated by Eaton's reagent, has been developed for the synthesis of Iasi-red polymethoxylated polycyclic aromatic hydrocarbons (PAHs). This route is currently the easiest method to obtain