875654-73-2

Basic information

• Product Name: 3''',4'''-anhydro-1,3,2',6',2''',6'''-hexa-N-(tert-butoxycarbonyl)-neomycin B
• Synonyms: 3''',4'''-anhydro-1,3,2',6',2''',6'''-hexa-N-(tert-butoxycarbonyl)-neomycin B
• CAS NO: 875654-73-2
• Molecular Weight: 1197.34
• Mol File: 875654-73-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3''',4'''-anhydro-1,3,2',6',2''',6'''-hexa-N-(tert-butoxycarbonyl)-neomycin B(CAS DataBase Reference)
• NIST Chemistry Reference: 3''',4'''-anhydro-1,3,2',6',2''',6'''-hexa-N-(tert-butoxycarbonyl)-neomycin B(875654-73-2)
• EPA Substance Registry System: 3''',4'''-anhydro-1,3,2',6',2''',6'''-hexa-N-(tert-butoxycarbonyl)-neomycin B(875654-73-2)

Safety Data

• Hazardous Substances Data: 875654-73-2(Hazardous Substances Data)

Upstream product

• 933770-22-0 3''',4'''-anhydro-1,3,2',6',2''',6'''-hexa-N-(tert-butoxycarbonyl)-5''-deoxy-5''-(4-nitrobenzoyl)neomycin 
• 241820-92-8 hexa-N-Boc neomycin B 
• 34619-03-9 tert-butyldicarbonate 

Downstream Products

• 1220984-37-1 C₅₃H₉₃N₉O₂₄ 

Relevant articles and documents

Mitsunobu dehydration of N-Boc neomycin B

Recation of hexa-N-boc neomycin B with triphenylphosphine (TPP), p-nitrobenzoic acid, and diisopropyl azodicarboxylate (DIAD) in toluene, which results in the formation of an epoxide in ring IV, was analyzed. Epoxide formation was favored by the trans-dia

Multisite modification of neomycin B: Combined Mitsunobu and click chemistry approach

The aminoglycoside antibiotic neomycin B has been converted into several novel building blocks that can be used for the specific modification of three of the four ring systems. Under carefully controlled conditions, the Mitsunobu reaction can be used to s