876-32-4

Basic information

• Product Name: 4-METHOXY-N-METHYLBENZYLAMINE HYDROCHLORIDE
• Synonyms: 4-METHOXY-N-METHYLBENZYLAMINE HYDROCHLORIDE;4-Methoxy-N-methylbenzylamineHCl95%;4-Methoxy-N-methylbenzylaminehydrochloride95%;4-Methoxy-N-methylbenzylamine hydrochloride 95%;4-Methoxy-n-MethylbenzylaMine, HCl;(4-Methoxyphenyl)-N-methylmethylamine hydrochloride, 4-[(Methylamino)methyl]anisole hydrochloride;Benzenemethanamine, 4-methoxy-N-methyl-;N-methyl-p-methoxybenzylamine
• CAS NO: 876-32-4
• Molecular Formula: C₉H₁₃NO*ClH
• Molecular Weight: 187.67
• Mol File: 876-32-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 176 °C
• Boiling Point: 261.2 °C at 760 mmHg
• Flash Point: 111.8 °C
• Appearance: /
• Vapor Pressure: 0.00919mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 4-METHOXY-N-METHYLBENZYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHOXY-N-METHYLBENZYLAMINE HYDROCHLORIDE(876-32-4)
• EPA Substance Registry System: 4-METHOXY-N-METHYLBENZYLAMINE HYDROCHLORIDE(876-32-4)

Safety Data

• Hazard Codes: C
• Hazardous Substances Data: 876-32-4(Hazardous Substances Data)

Usage

General Description

4-Methoxy-N-methylbenzylamine hydrochloride, also known as P-Methyl-N-methylbenzylamine hydrochloride, is a chemical compound with the molecular formula C9H14ClNO. It is a white crystalline powder that is soluble in water and ethanol. 4-METHOXY-N-METHYLBENZYLAMINE HYDROCHLORIDE is commonly used as a pharmaceutical intermediate in the synthesis of various drugs, including antidepressants and antihypertensive medications. It is also used in organic chemistry as a building block for the preparation of other important chemical compounds. In addition, 4-Methoxy-N-methylbenzylamine hydrochloride is known for its strong odor and should be handled with care in a well-ventilated area.

InChI:InChI=1/C9H13NO.ClH/c1-10-7-8-3-5-9(11-2)6-4-8;/h3-6,10H,7H2,1-2H3;1H

Upstream product

• 702-24-9 4-methoxy-N-methylbenzylamine 
• 1012879-33-2 3-(3-amino-4-fluorophenyl)-7-chloro-1-isopropyl-1,6-naphthyridin-2(1H)-one 

Downstream Products

• 55245-86-8 N‐[(4‐methoxyphenyl)methyl]‐N‐methylcarbamoyl chloride 
• 218900-31-3 N-(tert-butoxycarbonyl)-N-methyl(p-methoxybenzyl)amine 
• 1459695-18-1 C₂₄H₂₁ClF₂N₄O₃S 
• 1459695-33-0 C₂₅H₂₂ClF₂N₃O₄ 

Relevant articles and documents

DIHYDRONAPHTHYRIDINES AND RELATED COMPOUNDS USEFUL AS KINASE INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISEASES

The invention relates to dihydronaphthyridines and related compounds; compositions comprising an effective amount of a dihydronaphthyridine or a related compound; and methods for treating or preventing proliferative diseases comprising the administration of an effective amount of a dihydronaphthyridine or a related compound. The present invention discloses the unexpected utility of compounds that inhibit cKIT kinase across a broad range of c-KIT mutations, including complex occurrences of primary mutations (KIT exon 9 or 11) and secondary KIT mutations (exons 13, 14, 17 and 18) that may arise in individual, refractory GIST patients. Also unexpected is the utility of compounds of the present invention to inhibit the problematic exon 17 D816V c-KIT mutation, for which there is currently no effective therapy.