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3(4H)-QuinazolinebutanaMide, 2-aMino-N,g-dicyclohexyl-N-Methyl-6-phenoxy-, (hydrobroMide) (1:1), (gS)- , (HBr salt)
Cas No: 876761-22-7
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ZHEJIANG JIUZHOU CHEM CO.,LTD
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3(4H)-Quinazolinebutanamide, 2-amino-N,g-dicyclohexyl-N-methyl-6-phenoxy-, hydrobromide (1:1), (gS)- , (HBr salt)
Cas No: 876761-22-7
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Shanghai Haoyuan Chemexpress Co., Ltd.
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876761-22-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 876761-22-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,6,7,6 and 1 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 876761-22:
(8*8)+(7*7)+(6*6)+(5*7)+(4*6)+(3*1)+(2*2)+(1*2)=217
217 % 10 = 7
So 876761-22-7 is a valid CAS Registry Number.

876761-22-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	(4S)-4-(2-Amino-6-phenoxy-3(4H)-quinazolinyl)-N,4-dicyclohexyl-N- methylbutanamide hydrobromide (1:1)

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:876761-22-7 SDS

876761-22-7Upstream product

876761-22-7Downstream Products

876761-22-7Relevant articles and documents

2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (β-site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead

Baxter, Ellen W.,Conway, Kelly A.,Kennis, Ludo,Bischoff, Fran?ois,Mercken, Marc H.,De Winter, Hans L.,Reynolds, Charles H.,Tounge, Brett A.,Luo, Chi,Scott, Malcolm K.,Huang, Yifang,Braeken, Mirielle,Pieters, Serge M. A.,Berthelot, Didier J. C.,Masure, Stefan,Bruinzeel, Wouter D.,Jordan, Alfonzo D.,Parker, Michael H.,Boyd, Robert E.,Qu, Junya,Alexander, Richard S.,Brenneman, Douglas E.,Reitz, Allen B.

, p. 4261 - 4264 (2008/03/11)

A new aspartic protease inhibitory chemotype bearing a 2-amino-3,4- dihydroquinazoline ring was identified by high-throughput screening for the inhibition of BACE-1. X-ray crystallography revealed that the exocyclic amino group participated in a hydrogen

NOVEL 2-AMINO-QUINAZOLINE DERIVATIVES USEFUL AS INHIBITORS OF β-SECRETASE (BACE)

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Page/Page column 163, (2010/10/20)

The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer’s disease (AD) and related disorders. The compounds of the invention are inhibitors of β-secretase, also known as β-site cleaving enzyme and BACE.

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876761-22-7