877-79-2Relevant articles and documents
Compound, preparation method thereof and application of compound as fluorescent probe
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Paragraph 0110-0111; 0116, (2021/11/10)
The invention discloses a compound, a preparation method thereof and application of the compound as a fluorescent probe, wherein the compound I is selected from at least one compound of the chemical formula shown I. I In formula R1 . R2 Independently selected C1 - C5 Alkyl, C1 - C5 Alkoxy and substituted C1 - C5 At least one of the alkyl I of the alkyl group. R3 Be selected from C1 - C5 Alkyl groups. Substituted C1 - C5 At least one of the alkyl II groups of the alkyl group. The fluorescence probe provided by the invention can detect the morphology and the position of protein aggregation states through fluorescent imaging in living cells.
Synthesis of N-methyl imines in the presence of poly(N-vinylpyridine) as a reusable solid base catalyst by a mechanochemical process
Khaligh, Nader Ghaffari,Abbo, Hanna S.,Titinchi, Salam J. J.
, p. 901 - 910 (2017/02/10)
The synthesis of N-methyl imines was performed in the presence of catalytic amounts of poly(4-vinylpyridine) in high yields and rapidly at room temperature by a ball milling process. This new method has some advantages including good yields for relatively unreactive carbonyl compounds and short reaction times as well as being green in terms of avoiding the use of toxic reagents and solvents. The major advantage of this process is that the catalyst can be easily regenerated and reused several times without any significant loss of activity.
Efficient synthesis of new 4-arylideneimidazolin-5-ones related to the GFP chromophore by 2+3 cyclocondensation of arylideneimines with imidate ylides
Baldridge, Anthony,Kowalik, Janusz,Tolbert, Laren M.
scheme or table, p. 2424 - 2436 (2010/09/06)
A 2+3 condensation of a wide assortment of Schiff bases, prepared from aromatic aldehydes and primary amines, with methyl (1-ethoxyethylideneamino) acetate allows convenient access to an extensive family of substituted 4-arylideneimidazolin-5-one analogues of the green fluorescent protein (GFP) chromophore. Georg Thieme Verlag Stuttgart · New York.