878745-39-2

Basic information

• Product Name: 6-(5-(BOC-AMINO)-2-METHYLPHENYLAMINO)-3-METHYL-4-OXO-3,4-DIHYDROQUINAZOLINE
• Synonyms: 6-(5-(BOC-AMINO)-2-METHYLPHENYLAMINO)-3-METHYL-4-OXO-3,4-DIHYDROQUINAZOLINE
• CAS NO: 878745-39-2
• Molecular Formula: C₂₁H₂₄N₄O₃
• Molecular Weight: 380.44026
• Mol File: 878745-39-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-(5-(BOC-AMINO)-2-METHYLPHENYLAMINO)-3-METHYL-4-OXO-3,4-DIHYDROQUINAZOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(5-(BOC-AMINO)-2-METHYLPHENYLAMINO)-3-METHYL-4-OXO-3,4-DIHYDROQUINAZOLINE(878745-39-2)
• EPA Substance Registry System: 6-(5-(BOC-AMINO)-2-METHYLPHENYLAMINO)-3-METHYL-4-OXO-3,4-DIHYDROQUINAZOLINE(878745-39-2)

Safety Data

• Hazardous Substances Data: 878745-39-2(Hazardous Substances Data)

Upstream product

• 660838-05-1 t-butyl 3-amino-4-methylphenylcarbamate 
• 57573-59-8 6-bromo-3-N-methylquinazoline-4(3H)-one 
• 16064-09-8 6-chloro-3-methylquinazolin-4(3H)-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 119-32-4 4-Methyl-3-nitroanilin 
• 630410-29-6 (4-methyl-3-nitro-phenyl)-carbamic acid tert-butyl ester 
• 635-21-2 5-chloroanthranilic acid 
• 5794-88-7 5-Bromo-2-aminobenzoic acid 

Downstream Products

• 878745-42-7 6-(5-amino-2-methylphenylamino)-3-methylquinazolin-4(3H)-one 
• 1422175-99-2 C₂₇H₁₉F₄N₅O₃ 
• 1422176-00-8 C₂₇H₁₉F₄N₅O₃ 
• 1422175-70-9 C₂₇H₂₃FN₆O₄S 

Relevant articles and documents

PREPARATION AND METHODS OF USE FOR ORTHO-ARYL 5- MEMBERED HETEROARYL-CARBOXAMIDE CONTAINING MULTI-TARGETED KINASE INHIBITORS

The present disclosure relates to compounds of the Formula (I): and pharmaceutically acceptable salts, as kinase modulators, compatible with the Type-II inhibition of kinases.

SUBSTITUTED QUINAZOLINES WITH ANTI-CANCER ACTIVITY

The invention relates to chemical compounds of the formula (I): or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.