881853-81-2

Basic information

• Product Name: 2-[(R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionylamino]-3-methyl-2-trifluoromethyl-butyric acid ethyl ester
• CAS NO: 881853-81-2
• Molecular Weight: 490.479
• Mol File: 881853-81-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[(R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionylamino]-3-methyl-2-trifluoromethyl-butyric acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionylamino]-3-methyl-2-trifluoromethyl-butyric acid ethyl ester(881853-81-2)
• EPA Substance Registry System: 2-[(R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionylamino]-3-methyl-2-trifluoromethyl-butyric acid ethyl ester(881853-81-2)

Safety Data

• Hazardous Substances Data: 881853-81-2(Hazardous Substances Data)

Upstream product

• 3588-64-5 (R)-2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-3-phenylpropionic acid 
• 13081-18-0 ethyl-3,3,3-trifluoropyruvate 
• 126535-86-2 ethyl 2-(((benzyloxy)carbonyl)amino)-3,3,3-trifluoro-2-hydroxypropanoate 
• 126535-92-0 ethyl 2-{[(benzyloxy)carbonyl]imino}-3,3,3-trifluoropropanoate 
• 653587-69-0 (R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionyl bromide 

Downstream Products

• 881853-83-4 [5-benzyloxycarbonylamino-2-(2-{2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)-pent-4-enoylamino]-3-phenyl-propionylamino}-3-methyl-2-trifluoromethyl-butyrylamino)-pentanoylamino]-acetic acid tert-butyl ester 
• 881853-82-3 ((S)-5-Benzyloxycarbonylamino-2-{2-[(R)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionylamino]-3-methyl-2-trifluoromethyl-butyrylamino}-pentanoylamino)-acetic acid tert-butyl ester 
• 881853-84-5 ((S)-2-{2-[(R)-2-((S)-2-Amino-pent-4-enoylamino)-3-phenyl-propionylamino]-3-methyl-2-trifluoromethyl-butyrylamino}-5-benzyloxycarbonylamino-pentanoylamino)-acetic acid 
• 881853-85-6 [3-((2S,8S,11R)-8-Allyl-11-benzyl-14-isopropyl-3,6,9,12,15-pentaoxo-14-trifluoromethyl-1,4,7,10,13-pentaaza-cyclopentadec-2-yl)-propyl]-carbamic acid benzyl ester 

Relevant articles and documents

Incorporation of the unusual Cα-fluoroalkylamino acids into cyclopeptides: Synthesis of arginine-glycine-aspartate (RGD) analogues and study of their conformational and biological behavior

A series of six arginine-glycine-aspartate (RGD) cyclopeptide analogues containing a Cα-di- or trifluoromethylamino acid (α-Dfm or α-TfmAaa) at different positions of the ring were synthesized. All peptides were obtained in two diastereomeric f