88286-08-2

Basic information

• Product Name: 2-Aziridinecarboxamide, 3-(4-chlorophenyl)-, cis-
• CAS NO: 88286-08-2
• Molecular Formula: C9H9ClN2O
• Molecular Weight: 196.636
• Mol File: 88286-08-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Aziridinecarboxamide, 3-(4-chlorophenyl)-, cis-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Aziridinecarboxamide, 3-(4-chlorophenyl)-, cis-(88286-08-2)
• EPA Substance Registry System: 2-Aziridinecarboxamide, 3-(4-chlorophenyl)-, cis-(88286-08-2)

Safety Data

• Hazardous Substances Data: 88286-08-2(Hazardous Substances Data)

Upstream product

• 66864-57-1 2,3-dibromo-3-(4-chlorophenyl)propionitrile 
• 18166-64-8 4-chlorocinnamide 
• 88286-04-8 (2S,3S)-3-(4-Chloro-phenyl)-aziridine-2-carbonitrile 
• 114703-30-9 2,3,3-Trichloro-1-(4-chloro-phenyl)-prop-2-en-1-ol 
• 133474-01-8 1-(4-chlorophenyl)-2,3,3-trichloro-1-oxopropene 
• 1552-70-1 (Z)-methyl 3-(4-chlorophenyl)-2-chloropropenoate 

Downstream Products

• 80817-87-4 threo-3-fluoro-3-(4-chlorophenyl)alanine 
• 88286-25-3 threo-methyl 3-fluoro-3-(4-chlorophenyl)alanate 
• 88286-19-5 threo-2-amino-3-fluoro-3-(4-chlorophenyl)propionic acid amide 

Relevant articles and documents

Synthesis of α-Halocinnamate Esters via Solvolytic Rearrangement of Trichloroallyl Alcohols

Aryl trichlorovinyl ketones undergo regioselective reduction to the corresponding carbinols with sodium borohydride in alcoholic solvents and are transformed to the (Z)-α-chlorocinnamate ester derivatives via an acid-catalyzed allylic rearrangement.Micharl addition of ammonia to these ester derivatives affords cis- and/or trans-aziridine amides.The facile rearrangement allows the synthesis of d,l-phenylalanine derived from perchloroethylene and toluene.

REACTION OF HYDROGEN FLUORIDE IN PYRIDINE SOLUTION WITH CIS-CYANO-2 AND CIS-AMIDO-2-AZIRIDINES. PREPARATION OF β-FLUORO α-AMINO ACIDS AND ESTERS BY MEANS OF ACID HYDROLYSIS AND ALCOHOLYSIS OF β-FLUORO-α-AMINONITRILES AND/OR β-FLUORO-α-AMINO ACID AMIDES

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