88286-19-5

Basic information

• Product Name: threo-2-amino-3-fluoro-3-(4-chlorophenyl)propionic acid amide
• CAS NO: 88286-19-5
• Molecular Weight: 216.643
• Mol File: 88286-19-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: threo-2-amino-3-fluoro-3-(4-chlorophenyl)propionic acid amide(CAS DataBase Reference)
• NIST Chemistry Reference: threo-2-amino-3-fluoro-3-(4-chlorophenyl)propionic acid amide(88286-19-5)
• EPA Substance Registry System: threo-2-amino-3-fluoro-3-(4-chlorophenyl)propionic acid amide(88286-19-5)

Safety Data

• Hazardous Substances Data: 88286-19-5(Hazardous Substances Data)

Upstream product

• 66864-57-1 2,3-dibromo-3-(4-chlorophenyl)propionitrile 
• 88286-04-8 (2S,3S)-3-(4-Chloro-phenyl)-aziridine-2-carbonitrile 
• 88286-15-1 2-amino-3-fluoro-3-(4-chlorophenyl)propiononitrile 
• 88286-08-2 (2R,3R)-3-(4-Chloro-phenyl)-aziridine-2-carboxylic acid amide 
• 18166-64-8 4-chlorocinnamide 

Downstream Products

• 80817-87-4 threo-3-fluoro-3-(4-chlorophenyl)alanine 

Relevant articles and documents

Reaction of Hydrogen Fluoride in Pyridine Solution with cis-Cyano-2- and cis-Amido-2-aziridines. Preparation of β-Fluoro-α-amino Acids and Esters by Means of Acidic Hydrolysis and Alcoholysis of β-Fluoro-α-Amino Nitriles and/or β-Fluoro-α-Amino Acid Amide

The addition of hydrogen fluoride generated from pyridinium poly(hydrogen fluoride) (i.e.Olah's reagent) to some cis-2-cyano- and cis-2-amido-aziridines has been examined.The reaction led to fluoroamine derivatives which upon acidic hydrolysis and alcohol