883-34-1

Basic information

• Product Name: Imidazo[5,1-b]thiazole, 3-methyl-5-phenyl-
• CAS NO: 883-34-1
• Molecular Formula: C12H10N2S
• Molecular Weight: 214.291
• Mol File: 883-34-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Imidazo[5,1-b]thiazole, 3-methyl-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazo[5,1-b]thiazole, 3-methyl-5-phenyl-(883-34-1)
• EPA Substance Registry System: Imidazo[5,1-b]thiazole, 3-methyl-5-phenyl-(883-34-1)

Safety Data

• Hazardous Substances Data: 883-34-1(Hazardous Substances Data)

Upstream product

• 412284-34-5 N-(4-methyl-thiazol-2-ylmethyl)-benzamide 
• 7210-73-3 4-Methylthiazol-2-carbonsaeure-ethylester 
• 100-46-9 benzylamine 

Downstream Products

• 4626-45-3 6-phenylpyridine-2,3,4,5-tetracarboxylic acid-tetramethyl ester 
• 784-10-1 3-methyl-7-nitroso-5-phenyl-imidazo[5,1-b]thiazole 

Relevant articles and documents

Studies on Wallach's Imidazole Synthesis

The reaction of the N-benzylamides of N-heterocyclic carboxylic acids 3 and 6-9 with phosphorus pentachloride affords heterocondensed imidazoles 4 and 10-14 by a scheme reminiscent of Wallach's imidazole synthesis starting from N,N'-dialkyloxamides.Kinetic and labelling experiments are described which support a mechanism involving nitrile ylide species and allow a better understanding of the Wallach reaction.The limiting parameter for the formation of heteroanellated imidazoles is the electron availability of the heterocyclic ring.