885275-27-4 Usage
General Description
2-(Phenylmethyl)-2,7-diazaspiro[4.4]nonane, also known as Tropidine, is a chemical compound that belongs to the class of organic compounds known as tropanes. It is a bicyclic compound that contains a piperidine ring fused to a spiro[4.4]nonane moiety, with an additional phenylmethyl group attached to the piperidine ring. Tropidine has been used as a building block in the synthesis of various pharmaceuticals and biologically active compounds. Its unique structure and properties make it a valuable intermediate in organic synthesis and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 885275-27-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,7 and 5 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 885275-27:
(8*8)+(7*8)+(6*5)+(5*2)+(4*7)+(3*5)+(2*2)+(1*7)=214
214 % 10 = 4
So 885275-27-4 is a valid CAS Registry Number.
InChI:InChI=1/C14H20N2/c1-2-4-13(5-3-1)10-16-9-7-14(12-16)6-8-15-11-14/h1-5,15H,6-12H2
885275-27-4Relevant articles and documents
Preparation and characterization of N-(3-pyridinyl) spirocyclic diamines as ligands for nicotinic acetylcholine receptors
Sippy, Kevin B.,Anderson, David J.,Bunnelle, William H.,Hutchins, Charles W.,Schrimpf, Michael R.
scheme or table, p. 1682 - 1685 (2009/11/30)
Several N-pyridin-3-yl spirobicyclic diamines, designed as conformationally restricted analogs of tebanicline (ABT-594), were synthesized as novel ligands for nicotinic acetylcholine receptors (nAChR). The spirocyclic compounds exhibited weaker binding affinity, than other constrained analogs in accord with a pharmacophore model. Nevertheless, some (1a, 1b) possessed (partial) agonist potencies comparable to nicotine at the α4β2 subtype, but with greatly improved selectivity relative to the α3β4* nAChR.
