88530-32-9

Basic information

• Product Name: H-CYS(ACM)-NH2 HCL
• Synonyms: H-CYS(ACM)-NH2 HCL;(R)-3-(acetamidomethylthio)-2-aminopropanamide hydrochloride;REF DUPL: H-Cys(Acm)-NH2 HCl;S-((Acetamido)methyl)-L-cysteinamide;(2R)-3-[[(Acetylamino)methyl]thio]-2-aminopropanamide
• CAS NO: 88530-32-9
• Molecular Formula: C6H14ClN3O2S
• Molecular Weight: 227.71
• Product Categories: Amino Acids Derivatives;Cysteine [Cys, C];Amino Acids and Derivatives;Amino hydrochloride
• Mol File: 88530-32-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 497.8 °C at 760 mmHg
• Flash Point: 254.9 °C
• Appearance: /
• Vapor Pressure: 2.74E-10 mmHg at 25°C
• CAS DataBase Reference: H-CYS(ACM)-NH2 HCL(CAS DataBase Reference)
• NIST Chemistry Reference: H-CYS(ACM)-NH2 HCL(88530-32-9)
• EPA Substance Registry System: H-CYS(ACM)-NH2 HCL(88530-32-9)

Safety Data

• Hazardous Substances Data: 88530-32-9(Hazardous Substances Data)

Usage

General Description

H-CYS(ACM)-NH2 HCL, also known as N-acetyl-L-cysteine amide hydrochloride, is a chemical compound often used in the field of biochemistry and pharmaceutical research. It is a derivative of the amino acid cysteine and contains an acetyl group, which makes it more stable and easier to handle than the parent compound. This chemical is commonly used as a precursor in the synthesis of various cysteine-containing peptides and proteins and has been shown to have antioxidant and neuroprotective properties. Additionally, N-acetyl-L-cysteine amide hydrochloride is being studied for its potential therapeutic applications in the treatment of various medical conditions, including oxidative stress-related disorders and neurodegenerative diseases.

InChI:InChI=1S/C6H13N3O2S.ClH/c1-4(10)9-3-12-2-5(7)6(8)11;/h5H,2-3,7H2,1H3,(H2,8,11)(H,9,10);1H/t5-;/m0./s1

Upstream product

• 88530-31-8 N-t-Boc-Cys(Acm)-NH₂ 
• 19746-37-3 N-t-butoxycarbonyl-S-acetamidomethyl-L-cysteine 
• 58651-76-6 Boc-Cys(Acm)-ONp 

Relevant articles and documents

Hydrophobic parameters ? of amino-acid side chains from the partitioning of N-acetyl-amino-acid amides

A hydrophobic parameter for the side chain of each of the twenty naturally occuring amino-acids was estimated quantitatively by partitioning of their N-acetyl-amino-acid amides (CH3CO-NH-CH(R)-CONH2, R=variable side chain) in octanol/water.Suitable forms of the derivatives were synthesized chemically where necessary.The new series affords reliable distribution coefficients especially for polar amino-acids.A set of Hansch side chain parameters ? obtained for the twenty common amino-acids, for half-cystine as well as for the extremly lipophilic amino-acids carboranylalanine and adamantylalanine.It is found that these hydrophobicity indices, obtained at neutral pH, are tightly correlated with the degree of solvent exposure of the side chain in globular proteins and it is proposed that they be used in future biophysical and pharmacological studies.