886433-28-9Relevant articles and documents
Catalytic transient leaving group for atom-economic synthesis of allenes from 2-alkynols
Zhang, Wanli,Huang, Chaofan,Yuan, Yuan,Ma, Shengming
, p. 12430 - 12433 (2017)
An atom economic approach from readily available propargylic alcohols to allenes, the first carboxylation of propargylic alcohols, has been established. Through the cooperative binary catalysis of Pd and a phosphoric acid, the reaction afforded multi-substituted allenoates with a broad scope tolerating useful functional groups. The synthetic potential of the obtained products has been demonstrated.
Lanthanide-Catalyzed Reversible Alkynyl Exchange by Carbon–Carbon Single-Bond Cleavage Assisted by a Secondary Amino Group
Shao, Yinlin,Zhang, Fangjun,Zhang, Jie,Zhou, Xigeng
, p. 11485 - 11489 (2016/10/24)
Lanthanide-catalyzed alkynyl exchange through C?C single-bond cleavage assisted by a secondary amino group is reported. A lanthanide amido complex is proposed as a key intermediate, which undergoes unprecedented reversible β-alkynyl elimination followed by alkynyl exchange and imine reinsertion. The in situ homo- and cross-dimerization of the liberated alkyne can serve as an additional driving force to shift the metathesis equilibrium to completion. This reaction is formally complementary to conventional alkyne metathesis and allows the selective transformation of internal propargylamines into those bearing different substituents on the alkyne terminus in moderate to excellent yields under operationally simple reaction conditions.
1,2,3-Triazole: Unique ligand in promoting iron-catalyzed propargyl alcohol dehydration
Yan, Wuming,Ye, Xiaohan,Akhmedov, Novruz G.,Petersen, Jeffrey L.,Shi, Xiaodong
supporting information; experimental part, p. 2358 - 2361 (2012/06/18)
A 1,2,3-traizole-promoted iron(III)-catalyzed propargyl alcohol dehydration was developed for the synthesis of conjugated enynes. The desired conjugated enynes were prepared in good to excellent yields (up to 95%) with a large substrate scope and excellen