886845-10-9Relevant articles and documents
Reactions of 2-(α-haloalkyl)thiiranes with nucleophilic reagents: IV. Alkylation of sulfonamides with 2-chloromethylthiirane. Synthesis and properties of 3-(arylamino)thietanes
Sokolov,Butkevich,Yuskovets,Tomashevskii,Potekhin
, p. 1023 - 1035 (2007/10/03)
Alkylation of primary and secondary sulfonamides with 2- chloromethylthiirane in the presence of alkali gives the corresponding N-(thiiran-2-ylmethyl)- and/or N-(thietan-3-yl)sulfonamides. The selectivity of the process depends on the solvent: in water, t