889765-38-2

Basic information

• Product Name: (S)-3-Methyl-2-[2-((S)-1-phenyl-ethylamino)-ethylamino]-butan-1-ol
• Synonyms: (S)-3-Methyl-2-[2-((S)-1-phenyl-ethylamino)-ethylamino]-butan-1-ol
• CAS NO: 889765-38-2
• Molecular Weight: 250.384
• Mol File: 889765-38-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-Methyl-2-[2-((S)-1-phenyl-ethylamino)-ethylamino]-butan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-Methyl-2-[2-((S)-1-phenyl-ethylamino)-ethylamino]-butan-1-ol(889765-38-2)
• EPA Substance Registry System: (S)-3-Methyl-2-[2-((S)-1-phenyl-ethylamino)-ethylamino]-butan-1-ol(889765-38-2)

Safety Data

• Hazardous Substances Data: 889765-38-2(Hazardous Substances Data)

Upstream product

• 164219-31-2 ethyl (S)-2-oxo-2-((1-phenylethyl)amino)acetate 
• 2627-86-3 (S)-1-phenyl-ethylamine 

Relevant articles and documents

Design and synthesis of new bidentate alkoxy-NHC ligands for enantioselective copper-catalyzed conjugate addition

A new family of chiral alkoxy-N-heterocyclic carbene (NHC) ligands has been designed for the enantioselective copper-catalyzed conjugate addition of dialkylzincs to enones. These new bidentate NHC ligands were synthesized in high overall yields using a five-step procedure starting from commercially available β-aminoalcohols. Influence of the temperature, base, solvent and copper source were studied in order to optimize the stereoselectivity of the addition. High reactivity and excellent enantioselectivity were obtained at ambient temperature with a range of cyclic enones and dialkylzinc. Addition to acyclic enones has also been studied.