89284-38-8

Basic information

• Product Name: 3,5-Dichloro-2-Methylpyrazine
• Synonyms: 3,5-Dichloro-2-Methylpyrazine;3-Methyl-2,6-dichloropyrazine
• CAS NO: 89284-38-8
• Molecular Formula: C5H4Cl2N2
• Molecular Weight: 163.00466
• Mol File: 89284-38-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 202.6±35.0 °C(Predicted)
• Appearance: /
• Density: 1.404±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -2.33±0.10(Predicted)
• CAS DataBase Reference: 3,5-Dichloro-2-Methylpyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Dichloro-2-Methylpyrazine(89284-38-8)
• EPA Substance Registry System: 3,5-Dichloro-2-Methylpyrazine(89284-38-8)

Safety Data

• Hazardous Substances Data: 89284-38-8(Hazardous Substances Data)

Usage

General Description

3,5-Dichloro-2-Methylpyrazine is a chemical compound with the molecular formula C6H6Cl2N2. It is a derivative of pyrazine, containing two chlorine atoms and a methyl group attached to the pyrazine ring. 3,5-Dichloro-2-Methylpyrazine is commonly used in the food industry as a flavoring agent, adding a nutty and roasted flavor to products such as coffee, cocoa, and bread. It is also used in the pharmaceutical and agricultural industries as an intermediate in the synthesis of various drugs and agrochemicals. 3,5-Dichloro-2-Methylpyrazine is considered to be a relatively low-toxicity chemical, with no known significant health hazards associated with its use in regulated quantities. However, it should still be handled with caution and in accordance with proper safety protocols.

Upstream product

• 4774-14-5 2,6-dichloropyrazine 
• 74-88-4 methyl iodide 

Downstream Products

• 1430460-55-1 N-benzyl-6-chloro-3-methylpyrazin-2-amine 
• 1430460-76-6 N-benzyl-6-chloro-5-methylpyrazin-2-amine 

Relevant articles and documents

BIARYL DERIVATIVE AS GPR120 AGONIST

The present invention relates to a biaryl derivative expressed by the chemical formula 1, a method for producing the biaryl derivative, a pharmaceutical composition comprising same, and use of same, the biaryl derivative expressed by the chemical formula 1, as a GPR120 agonist, promoting GLP-1 generation in the gastro-intestinal tract, reducing insulin resistance in the liver, muscles and the like from anti-inflammatory activity in the macrophage, pancreatic cells and the like, and allowing effective use in prevention or treatment of inflammation or metabolic diseases such as diabetes, complications from diabetes, obesity, non-alcoholic fatty liver disease, fatty liver disease, and osteoporosis.

6 SUBSTITUTED 2-HETEROCYCLYLAMINO PYRAZINE COMPOUNDS AS CHK-1 INHIBITORS

The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, their synthesis, and their use as CHK-1 inhibitors.

PYRAZINE-BASED TUBULIN INHIBITORS

A compound of general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof is described. A method of treating a hyperproliferation-related disease state or disorder in a subject using a compound of formula (I) is also described