89781-52-2

Basic information

• Product Name: 8-OXO-5,6,7,8-TETRAHYDRO-NAPHTHALENE-2-CARBOXYLIC ACID
• Synonyms: 8-oxo-6,7-dihydro-5H-naphthalene-2-carboxylic acid;5,6,7,8-tetrahydro-8-oxo-2-Naphthalenecarboxylic acid
• CAS NO: 89781-52-2
• Molecular Formula: C11H10O3
• Molecular Weight: 190.2
• Mol File: 89781-52-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 216 °C
• Boiling Point: 389.1±31.0 °C(Predicted)
• Appearance: /
• Density: 1.309±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.97±0.20(Predicted)
• CAS DataBase Reference: 8-OXO-5,6,7,8-TETRAHYDRO-NAPHTHALENE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 8-OXO-5,6,7,8-TETRAHYDRO-NAPHTHALENE-2-CARBOXYLIC ACID(89781-52-2)
• EPA Substance Registry System: 8-OXO-5,6,7,8-TETRAHYDRO-NAPHTHALENE-2-CARBOXYLIC ACID(89781-52-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 89781-52-2(Hazardous Substances Data)

Usage

Description

8-OXO-5,6,7,8-TETRAHYDRO-NAPHTHALENE-2-CARBOXYLIC ACID, also known as 5,6,7,8-Tetrahydro-8-oxo-2-naphthoic Acid, is a chemical compound with potential therapeutic applications. It is characterized by its unique molecular structure, which includes a naphthalene core with a carboxylic acid group and an oxo group at the 8-position. 8-OXO-5,6,7,8-TETRAHYDRO-NAPHTHALENE-2-CARBOXYLIC ACID has been identified for its potential role in treating cancer and other Pin1-associated conditions.

Uses

Used in Pharmaceutical Industry:
8-OXO-5,6,7,8-TETRAHYDRO-NAPHTHALENE-2-CARBOXYLIC ACID is used as a therapeutic agent for treating cancer and other Pin1-associated conditions. Its application is based on its ability to target and modulate the activity of Pin1, a peptidyl-prolyl isomerase enzyme that plays a crucial role in cell cycle regulation and has been implicated in the development and progression of various cancers. By inhibiting Pin1, this compound may help to prevent the growth and spread of cancer cells, offering a potential treatment option for patients with cancer and other Pin1-associated diseases.

Upstream product

• 34162-06-6 4-(3-carboxypropyl)benzoic acid 
• 10031-93-3 ethyl 4-phenylbutyrate 
• 71665-59-3 4-(4-acetylphenyl)butyric acid ethyl ester 
• 100117-48-4 4-(4-acetylphenyl)butanoic acid 
• 124-38-9 carbon dioxide 
• 111773-13-8 7-Bromo-1,2,3,4-tetrahydronaphthalene-1-spiro-2'-(1',3'-dioxacyclopentane) 

Downstream Products

• 116047-26-8 methyl 8-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylate 
• 130532-67-1 8-(Hydroxyimino)-5,6,7,8-tetrahydronaphth-2-oic Acid 
• 130532-76-2 (RS)-8-<(tert-Butoxy)carbonylamino>-5,6,7,8-tetrahydronaphtho-2-oic Acid 
• 130532-64-8 (RS)-8-Amino-5,6,7,8-tetrahydronaphth-2-oic Acid Hydrochloride 
• 130540-25-9 HCl*H-Amn-Lys(Z)-Gly-OMe 
• 152768-98-4 8-(Aminomethyl)naphth-2-oic Acid Hydrochloride 
• 152769-04-5 8-[((S)-4-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-butyrylamino)-methyl]-naphthalene-2-carboxylic acid 
• 152769-03-4 8-[((S)-4-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-butyrylamino)-methyl]-naphthalene-2-carboxylic acid methyl ester 
• 152769-06-7 (S)-8-[((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-methyl]-5,6,7,8-tetrahydro-naphthalene-2-carboxylic acid 
• 152769-05-6 (S)-8-[((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-methyl]-5,6,7,8-tetrahydro-naphthalene-2-carboxylic acid methyl ester 
• 152768-79-1 Boc-Amn-Glu(OBzl)-Gly-OAll 
• 152769-07-8 Boc-Amn-Dab(Z)-Gly-OMe 
• 152768-72-4 Boc-Amn-Lys(Z)-Gly-OMe 
• 152769-09-0 Boc-(R)-Amhn-Lys(Z)-Gly-OMe 

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