897932-09-1Relevant articles and documents
Design, synthesis, and biological evaluation of chicoric acid analogs as inhibitors of HIV-1 integrase
Charvat, Trevor T.,Lee, Deborah J.,Robinson, W. Edward,Chamberlin, A. Richard
, p. 4552 - 4567 (2007/10/03)
A series of analogs of the potent HIV-1 integrase (HIV IN) inhibitor chicoric acid (CA) was designed with the intention of ameliorating some of the parent natural product's undesirable properties, in particular its toxicity, instability, and poor membrane