900811-45-2Relevant articles and documents
Formal total synthesis of the potent renin inhibitor aliskiren: Application of a SmI2-promoted acyl-like radical coupling
Lindsay, Karl B.,Skrydstrup, Troels
, p. 4766 - 4777 (2007/10/03)
A formal total synthesis of the potent renin inhibitor aliskiren is disclosed exploiting an alternative coupling strategy recently developed by this laboratory for the preparation of the hydroxyethylene isostere-based class of protease inhibitors. The thi