90296-22-3

Basic information

• Product Name: Propanedioic acid, [2-(4-bromophenoxy)ethyl]-, diethyl ester
• CAS NO: 90296-22-3
• Molecular Formula: C15H19BrO5
• Molecular Weight: 359.217
• Mol File: 90296-22-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, [2-(4-bromophenoxy)ethyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, [2-(4-bromophenoxy)ethyl]-, diethyl ester(90296-22-3)
• EPA Substance Registry System: Propanedioic acid, [2-(4-bromophenoxy)ethyl]-, diethyl ester(90296-22-3)

Safety Data

• Hazardous Substances Data: 90296-22-3(Hazardous Substances Data)

Upstream product

• 34743-88-9 2-(4-bromophenoxy)ethanol 
• 106-41-2 4-bromo-phenol 
• 18800-30-1 1-bromo-4-(2-bromoethoxy)benzene 
• 105-53-3 diethyl malonate 
• 55162-34-0 1-bromo-4-(2-chloroethoxy)benzene 

Downstream Products

• 90296-21-2 2-<2-(p-bromophenoxy)ethyl>malonic acid 

Relevant articles and documents

Structure-activity studies of 3-benzoylpropionic acid derivatives suppressing adjuvant arthritis

3-Benzoylpropionic acid derivatives possess an immunomodulative activity and suppress adjuvant arthritis. To understand how substituents affect the biological activity, the quantitative structure-activity relationships of 30 compounds were analyzed by the adaptive least-squares method. For the suppressing activity in rats, the electronic effects and the structural feature of the substituent on benzene ring were suggested to be important. To reinforce and confirm the correlation, 4 additional compounds of phenoxybutyric acid derivatives were synthesized and tested with the rat adjuvant-induced arthritis. These compounds were found to have potent suppressing activity.