90696-12-1

Basic information

• Product Name: 2-Azetidinone, 1-(4-methoxyphenyl)-3-(1-methylethyl)-4-phenyl-, cis-
• CAS NO: 90696-12-1
• Molecular Formula: C19H21NO2
• Molecular Weight: 295.381
• Mol File: 90696-12-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Azetidinone, 1-(4-methoxyphenyl)-3-(1-methylethyl)-4-phenyl-, cis-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azetidinone, 1-(4-methoxyphenyl)-3-(1-methylethyl)-4-phenyl-, cis-(90696-12-1)
• EPA Substance Registry System: 2-Azetidinone, 1-(4-methoxyphenyl)-3-(1-methylethyl)-4-phenyl-, cis-(90696-12-1)

Safety Data

• Hazardous Substances Data: 90696-12-1(Hazardous Substances Data)

Upstream product

• 108-64-5 Ethyl isovalerate 
• 783-08-4 [4-(benzylideneamino)phenyl]methanol 
• 139007-44-6 S-(2-pyridinyl) 3-methylbutanethioate 

Relevant articles and documents

Optically active aminoalcohol promoted addition of 2-pyridylthioester boron enolates to imines: Enantioselective one-pot synthesis of β-lactams

The enolates derived from 2-pyridylthioesters by treatment with BCl3·Me2S and enantiomerically pure aminoalcohols react with aromatic and heteroaromatic imines to afford β-lactams in a convenient one-pot procedure and in up to 78% e.

Synthesis of β-lactams by condensation of the tin enolates of 2-pyridylthioesters with imines. A comparison between titanium and tin enolates

Addition of triethylamine to a mixture of 2-pyridylthioesters and SnCl4 or SnBr4 affords the corresponding tin(IV) enolates that add to imines to give β-lactams in fair to good yields and with various degree of trans/cis stereoselectivity. Examples of highly diastereofacially selective reactions carried out on a chiral thioester and on a chiral imine are also reported. The results are compared with those obtained in the condensations promoted by TiCl4 and TiBr4.