909527-60-2

Basic information

• Product Name: N-methyl-4-(trifluoromethoxy)benzenesulfonamide
• Synonyms: N-methyl-4-(trifluoromethoxy)benzenesulfonamide
• CAS NO: 909527-60-2
• Molecular Weight: 255.218
• Mol File: 909527-60-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: N-methyl-4-(trifluoromethoxy)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-4-(trifluoromethoxy)benzenesulfonamide(909527-60-2)
• EPA Substance Registry System: N-methyl-4-(trifluoromethoxy)benzenesulfonamide(909527-60-2)

Safety Data

• Hazardous Substances Data: 909527-60-2(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 1513-45-7 p-(trifluoromethoxy)benzenesulfonamide 

Downstream Products

• 1620220-75-8 C₁₂H₁₂F₃NO₄S 

Relevant articles and documents

Recyclable covalent triazine framework-supported iridium catalyst for the N-methylation of amines with methanol in the presence of carbonate

An iridium complex Cp*Ir@CTF, which is synthesized by the coordinative immobilization of [Cp*IrCl2]2 on a functionalized covalent triazine framework (CTF), was found to be a general and highly efficient catalyst for the N-methylation of amines with methanol in the presence of carbonate. Under environmentally benign conditions, a variety of desirable products were obtained in high yields with complete selectivities and functional group friendliness. Furthermore, the synthesized catalyst could be recycled by simple filtration without obvious loss of catalytic activity after sixth cycle. Notably, this research exhibited the potential of covalent triazine framework-supported transition metal catalysts for hydrogen autotransfer process.

Method for synthesizing N-methyl sulfonamide in water

The invention discloses a method N - for synthesizing,methylsulfamide in water, by using a transition metal iridium catalyst to catalyze N - methylation reaction. by using a non-toxic and harmless water as a solvent, to avoid using the organic agent; to react only as a byproduct, without an environmental hazard; reaction temperature with respect to the previous strip more mild; and have a wide application prospect; with high selectivity, reaction atomic economy.

N-Methylation of Amines with Methanol Catalyzed by a Cp?Ir Complex Bearing a Functional 2,2′-Bibenzimidazole Ligand

A new type of Cp?Ir complex bearing a functional 2,2′-bibenzimidazole ligand was designed, synthesized, and found to be a highly effective and general catalyst for the N-methylation of a variety of amines with methanol in the presence of a weak base (0.3 equiv of Cs2CO3).