1513-45-7

Basic information

• Product Name: 4-(Trifluoromethoxy)benzenesulfonamide
• Synonyms: 4-(TRIFLUOROMETHOXY)BENZENESULFONAMIDE;4-(TRIFLUOROMETHOXY)BENZENESULPHONAMIDE;BUTTPARK 21\07-20;4-Trifluoromethoxybenzenesulphonyl amine;4-trifluoromethoxybenzensulfonamide;Jrd-1772;4-(trifluoroMethoxy)benzene-1-sulfonaMide
• CAS NO: 1513-45-7
• Molecular Formula: C₇H₆F₃NO₃S
• Molecular Weight: 241.19
• EINECS: -0
• Product Categories: Organic Building Blocks;Sulfonamides/Sulfinamides;Sulfur Compounds
• Mol File: 1513-45-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 146-148 °C(lit.)
• Boiling Point: 301.8 °C at 760 mmHg
• Flash Point: 136.3 °C
• Appearance: /
• Density: 1.519 g/cm³
• Vapor Pressure: 0.00103mmHg at 25°C
• Refractive Index: 1.49
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: 9.81±0.10(Predicted)
• BRN: 2653449
• CAS DataBase Reference: 4-(Trifluoromethoxy)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Trifluoromethoxy)benzenesulfonamide(1513-45-7)
• EPA Substance Registry System: 4-(Trifluoromethoxy)benzenesulfonamide(1513-45-7)

Safety Data

• Hazard Codes: Xi
• Statements: 22-36/37/38
• Safety Statements: 22-36/37-37-26
• WGK Germany: 3
• Hazardous Substances Data: 1513-45-7(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C7H6F3NO3S/c8-7(9,10)14-5-1-3-6(4-2-5)15(11,12)13/h1-4H,(H2,11,12,13)

Upstream product

• 94108-56-2 4-(trifluoro-methoxy)benzene-1-sulfonyl chloride 

Downstream Products

• 882996-95-4 C₃₀H₂₇F₃N₂O₅S 
• 909523-50-8 N-benzyl-4-(trifluoromethoxy)benzenesulfonamide 
• 1361001-35-5 (E)-2-(5-fluoro-1-(4-(methylthio)benzylidene)-1H-inden-3-yl)-N-(4-(trifluoromethoxy)phenylsulfonyl)acetamide 
• 1422358-93-7 C₁₉H₁₃F₄N₃O₃S 
• 1427215-10-8 C₂₇H₂₂ClF₃N₂O₆S 
• 1427214-89-8 C₂₅H₁₈ClF₃N₂O₆S 
• 909527-60-2 N-methyl-4-(trifluoromethoxy)benzenesulfonamide 

Relevant articles and documents

Electrochemically generatedN-iodoaminium species as key intermediates for selective methyl sulphonylimination of tertiary amines

Reported herein is a straightforward protocol for approachingN-sulphonylamidinesviaan electricity-driven, iodine-mediated cross dehydrogenative condensation (CDC) between sulphonamides and tertiary amines, which features exclusive N-CH3selectivity for the amine partners. Mechanistic studies indicate that anin situgeneratedN-iodoaminium species serves as the key intermediate.

N-acyl sulfamide FBPase inhibitor, preparation method thereof, drug composition and application

The invention discloses an N-acryl sulfamide FBPase inhibitor of a novel structure, and a preparation method thereof, a drug composition and an application, and particularly relates to an N-acryl sulfamide FBPase inhibitor shown in the formula I, a salt thereof for medicine, a preparation method, a composition comprising one or more compounds, an application of the compound in preparing the FBPase inhibitor or a drug for treating FBPase-related diseases, and an application in preparing a drug for preventing and/or treating diabetes. The formula is shown in the description.

Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals

The invention relates to sulfonamido- and sulfonamido-carbonylpyridine-2-carboxa of the formula I STR1 and their use as pharmaceuticals, in particular against fibrotic diseases.