91084-05-8

Basic information

• Product Name: L-Phenylalanine, N-(ethoxycarbonyl)-, methyl ester
• CAS NO: 91084-05-8
• Molecular Formula: C13H17NO4
• Molecular Weight: 251.282
• Mol File: 91084-05-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-(ethoxycarbonyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-(ethoxycarbonyl)-, methyl ester(91084-05-8)
• EPA Substance Registry System: L-Phenylalanine, N-(ethoxycarbonyl)-, methyl ester(91084-05-8)

Safety Data

• Hazardous Substances Data: 91084-05-8(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 63-91-2 L-phenylalanine 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 1363553-29-0 (S)-methyl 2-((2-(chloromethyl)-4,5-dimethoxybenzyl)(ethoxycarbonyl)amino)-3-phenylpropanoate 
• 1363553-23-4 (S)-methyl 2-(5,6-dimethoxyisoindolin-2-yl)-3-phenylpropanoate 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 212514-45-9 (S)-6-Ethoxycarbonylamino-5-oxo-7-phenyl-4-(toluene-4-sulfonyl)-heptanoic acid ethyl ester 
• 212514-42-6 (S)-5-Ethoxycarbonylamino-4-oxo-6-phenyl-3-(toluene-4-sulfonyl)-hexanoic acid ethyl ester 
• 212514-44-8 [(S)-1-Benzyl-2-oxo-4-phenyl-3-(toluene-4-sulfonyl)-butyl]-carbamic acid ethyl ester 
• 212514-43-7 [(S)-1-Benzyl-2-oxo-3-(toluene-4-sulfonyl)-hex-5-enyl]-carbamic acid ethyl ester 
• 871210-15-0 (2S,3R)-2-(ethoxycarbonylamino)-6,6,7,7,8,8,9,9,10,10,11,11,11-tridecafluoro-1-phenyl-undecan-3-ol 
• 871210-26-3 (2S,3R)-2-amino-6,6,7,7,8,8,9,9,10,10,11,11,11-tridecafluoro-1-phenyl-undecan-3-ol 
• 857637-92-4 (4S,5R)-4-benzyl-5-(1'H,1'H,2'H,2'H-perfluorooctyl)-oxazolidin-2-one 
• 212514-39-1 [(S)-1-Benzyl-2-oxo-3-(toluene-4-sulfonyl)-propyl]-carbamic acid ethyl ester 
• 161646-29-3 (S)-ethyl (1-hydroxy-3-phenylpropan-2-yl)carbamate 
• 95205-30-4 methyl N-ethoxycarbonyl-N-nitrosophenylalaninate 
• 91083-96-4 Methyl N-(ethoxycarbonyl)-N,p-dinitrophenylalaninate 
• 871210-02-5 2(S)-(ethoxycarbonylamino)-6,6,7,7,8,8,9,9,10,10,11,11,11-tridecafluoro-1-phenyl-undecan-3-one 
• 871210-08-1 2(S)-(ethoxycarbonylamino)-3,3-bis(1'H,1'H,2'H,2'H-perfluorooctyl)-1-phenyl-propan-3-ol 
• 393516-55-7 (S)-1,1-dibromo-3-(ethoxycarbonyl)amino-2-oxo-4-phenylbutane 

Relevant articles and documents

Urethanes synthesis from oxamic acids under electrochemical conditions

Urethane synthesis via oxidative decarboxylation of oxamic acids under mild electrochemical conditions is reported. This simple phosgene-free route to urethanes involves an in situ generation of isocyanates by anodic oxidation of oxamic acids in an alcoholic medium. The reaction is applicable to a wide range of oxamic acids, including chiral ones, and alcohols furnishing the desired urethanes in a one-pot process without the use of a chemical oxidant.

1,2-Dimethoxy-4,5-dimethylene: A new protecting group for acyclic amino acid derivatives prepared by Stevens rearrangement

A new protecting group, 1,2-dimethoxy-4,5-dimethylene, for acyclic amino acid derivatives could be introduced by N,N-dialkylation with 1,2-bis(bromomethyl)-4,5-dimethoxybenzene (1) and removed via amine de-alkylation with acyl chlorides. The method can be used with base-induced [2,3] and [1,2] Stevens rearrangement products.

Practical synthesis of fluorous oxazolidinone chiral auxiliaries from α-amino acids

A series of new fluorous-supported oxazolidinone chiral auxiliaries has been prepared using a versatile and general five-step pathway, starting from readily available chiral α-amino acids. The key feature of this synthesis is the efficient generation of a suitably active perfluoroalkyllithium species. By use of this protocol, the auxiliaries can be obtained in high enantiomeric purity and on multigram scales from L-phenylalanine and L-valine with overall yields as high as 55%. The new methodology also incorporates fluorous solid-phase extraction on the large scale, allowing bulk quantities (up to 25 g) of fluorous compounds to be purified from the crude reaction mixture.