911825-55-3

Basic information

• Product Name: methyl 4-(2-fluorophenyl)butanoate
• Synonyms: methyl 4-(2-fluorophenyl)butanoate
• CAS NO: 911825-55-3
• Molecular Weight: 196.221
• Mol File: 911825-55-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 4-(2-fluorophenyl)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(2-fluorophenyl)butanoate(911825-55-3)
• EPA Substance Registry System: methyl 4-(2-fluorophenyl)butanoate(911825-55-3)

Safety Data

• Hazardous Substances Data: 911825-55-3(Hazardous Substances Data)

Upstream product

• 3724-55-8 methyl but-3-enoate 
• 348-52-7 1-Fluoro-2-iodobenzene 
• 292638-85-8 acrylic acid methyl ester 
• 401514-50-9 o-fluorobenzaldehyde hydrazone 
• 446-52-6 2-Fluorobenzaldehyde 

Downstream Products

• 166251-26-9 4-(2-fluorophenyl)butyryl chloride 
• 93742-85-9 5-fluoro-3,4-dihydronaphthalen-1(2H)-one 
• 911825-56-4 5-fluoro-3,4-dihydronaphthalen-1(2H)-one oxime 
• 907973-43-7 5-fluoro-1,2,3,4-tetrahydronaphthalen-1-amine 
• 143654-62-0 4-(2-Fluorophenyl)butanoic acid 

Relevant articles and documents

Copper-Catalyzed Conjugate Addition of Carbonyls as Carbanion Equivalent via Hydrazones

Copper-catalyzed conjugate addition is a classic method for forming new carbon-carbon bonds. However, copper has never showed catalytic activity for umpolung carbanions in hydrazone chemistry. Herein, we report a facile conjugate addition of hydrazone catalyzed by readily available copper complexes at room temperature. The employment of mesitylcopper(I) and electron-rich phosphine bidentate ligand is a key factor affecting reactivity. The reaction allows various aromatic hydrazones to react with diverse conjugated compounds to produce 1,4-adducts in yields of about 20 to 99%.

7-SUBSTITUTED PURINE DERIVATIVES FOR IMMUNOSUPPRESSION

The present invention provides novel purinone and related derivatives useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection. The compounds are of the general formula (III).