91350-79-7

Basic information

• Product Name: 2-cyano-3-(4-methoxy-phenyl)-propionic acid amide
• Synonyms: 2-cyano-3-(4-methoxy-phenyl)-propionic acid amide
• CAS NO: 91350-79-7
• Molecular Weight: 204.228
• Mol File: 91350-79-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-cyano-3-(4-methoxy-phenyl)-propionic acid amide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyano-3-(4-methoxy-phenyl)-propionic acid amide(91350-79-7)
• EPA Substance Registry System: 2-cyano-3-(4-methoxy-phenyl)-propionic acid amide(91350-79-7)

Safety Data

• Hazardous Substances Data: 91350-79-7(Hazardous Substances Data)

Upstream product

• 7664-41-7 ammonia 
• 123-11-5 4-methoxy-benzaldehyde 
• 105-56-6 ethyl 2-cyanoacetate 
• 107-91-5 cyanoacetic acid amide 
• 100-66-3 methoxybenzene 
• 7324-84-7 3-(4-methoxyphenyl)-2-cyanopropenamide 
• 5553-92-4 2-(4-methoxybenzyl)malononitrile 

Downstream Products

• 7324-84-7 3-(4-methoxyphenyl)-2-cyanopropenamide 

Relevant articles and documents

Room Temperature, Reductive Alkylation of Activated Methylene Compounds: Carbon-Carbon Bond Formation Driven by the Rhodium-Catalyzed Water-Gas Shift Reaction

The rhodium-catalyzed water-gas shift reaction has been demonstrated to drive the reductive alkylation of several classes of activated methylene compounds at room temperature. Under catalysis by rhodium trichloride (2-3 mol %), carbon monoxide (10 bar), water (2-50 equiv), and triethylamine (2.5-7 equiv), the scope has been successfully expanded to cover a wide range of alkylating agents, including aliphatic and aromatic aldehydes, as well as cyclic ketones, in moderate to high yields. This method is comparable to, and for certain aspects, surpasses the established reductive alkylation protocols.