5553-92-4

Basic information

• Product Name: 2-(4-METHOXYBENZYL)MALONONITRILE
• Synonyms: RARECHEM AL BY 0082;2-(4-METHOXYBENZYL)MALONONITRILE
• CAS NO: 5553-92-4
• Molecular Formula: C₁₁H₁₀N₂O
• Molecular Weight: 186.21
• Mol File: 5553-92-4.mol
• Article Data: 27

Chemical Properties

• Melting Point: 88-91°C
• Boiling Point: 406.8°Cat760mmHg
• Flash Point: 174.1°C
• Appearance: /
• Density: 1.08g/cm³
• Vapor Pressure: 5.54E-06mmHg at 25°C
• Refractive Index: 1.531
• CAS DataBase Reference: 2-(4-METHOXYBENZYL)MALONONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-METHOXYBENZYL)MALONONITRILE(5553-92-4)
• EPA Substance Registry System: 2-(4-METHOXYBENZYL)MALONONITRILE(5553-92-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 5553-92-4(Hazardous Substances Data)

Usage

General Description

2-(4-Methoxybenzyl)malononitrile is a chemical compound with the molecular formula C13H11NO2. It is a white to off-white crystalline solid, and is known for its use in organic synthesis, especially in the production of pharmaceuticals and agrochemicals. The compound contains a benzyl group substituted with a methoxy group and is part of the malononitrile family, which is commonly used as a building block in organic chemistry. It has a wide range of applications due to its reactivity and stability, and is commonly used as an intermediate in the synthesis of various organic compounds. Additionally, it has been researched for its potential biological and pharmaceutical activities.

InChI:InChI=1/C11H10N2O/c1-14-11-4-2-9(3-5-11)6-10(7-12)8-13/h2-5,10H,6H2,1H3

Upstream product

• 922-64-5 1,1-dicyanoethylene 
• 100-66-3 methoxybenzene 
• 16015-95-5 (4-methoxy-benzyl)-malonic acid diamide 
• 2826-26-8 2-(4-methoxyphenylmethylene)malononitrile 
• 1450-14-2 1,1,1,2,2,2-hexamethyldisilane 
• 95-54-5 1,2-diamino-benzene 
• 1149-23-1 diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 109-77-3 malononitrile 
• 123-11-5 4-methoxy-benzaldehyde 
• 6335-37-1 2-(4-methoxybenzyl)malonic acid diethyl ester 
• 2637-34-5 2-Sulfanylpyridine 
• 3001-72-7 DBN 

Downstream Products

• 91350-79-7 2-cyano-3-(4-methoxy-phenyl)-propionic acid amide 
• 6731-49-3 bromo-(4-methoxy-benzyl)-malononitrile 
• 21405-62-9 2-(4-methoxybenzyl)malonic acid 
• 338965-05-2 5-(4-methoxy-benzyl)-pyrimidine-2,4,6-triyltriamine 
• 109547-66-2 4-(4-Methoxy-benzyl)-isoxazole-3,5-diamine 
• 138573-99-6 3-(4-Methoxy-benzoyl)-1,4-diaza-spiro[4.5]dec-3-en-2-one 
• 163590-19-0 3,5-diamino-4-(4-methoxybenzyl)-1H-pyrazole 
• 533928-83-5 2-(4-methoxybenzyl)-2-methylmalononitrile 
• 1929-29-9 3-(4-methoxyphenyl)propanoic acid 
• 1333147-87-7 2-(tert-butylperoxy)-2-(4-methoxybenzyl)malononitrile 
• 338965-07-4 5-(4-Methoxy-benzyl)-2-pyridin-2-yl-pyrimidine-4,6-diamine 
• 2826-26-8 2-(4-methoxyphenylmethylene)malononitrile 
• 1607831-20-8 [8-(4-methoxybenzyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrazolo[1,5-a][1,3,5]triazin-7-yl]thiourea 
• 1607831-48-0 C₁₉H₂₄N₆O₅S₂ 

Relevant articles and documents

Direct Cyclopropanation of α-Cyano β-Aryl Alkanes by Light-Mediated Single Electron Transfer Between Donor–Acceptor Pairs

Cyclopropanes are traditionally prepared by the formal [2+1] addition of carbene or radical based C1 units to alkenes. In contrast, the one-pot intermolecular cyclopropanation of alkanes by redox active C1 units has remained unrealised. Herein, we achieve

Tandem Condensation-Hydrogenation to Produce Alkylated Nitriles Using Bifunctional Catalysts: Platinum Nanoparticles Supported on MOF-Derived Carbon

Tandem catalysis, which allows multiple steps of a reaction to take place without the need for separation and purification, is highly desired for the design of efficient and environmentally-friendly chemical processes. Herein, the pyrolysis of UiO-66-NHs

Mechanistic Investigations of Reactions of the Frustrated Lewis Pairs (Triarylphosphines/B(C6F5)3) with Michael Acceptors

Frustrated Lewis pair (FLP)-catalyzed reduction of Michael acceptors is a challenging reaction that proceeds with specific FLP structures. Kinetics and equilibrium of the reactions of two phosphines (Ar3P), namely tri(1-naphthyl)phosphine and tri(o-tolyl)phosphine, are reported with reference electrophiles. The reason for the failure of the FLPs (Ar3P/B(C6F5)3) to reduce activated alkenes under H2 pressure is shown to be a hydrophosphination process that inhibits the reduction reaction. Kinetic and thermodynamic factors controlling both pathways are discussed in light of Mayr's free linear energy relationships.