914654-71-0

Basic information

• Product Name: Hydrazine, 1-(3-fluorophenyl)-1-phenyl-
• CAS NO: 914654-71-0
• Molecular Formula: C12H11FN2
• Molecular Weight: 202.231
• Mol File: 914654-71-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Hydrazine, 1-(3-fluorophenyl)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazine, 1-(3-fluorophenyl)-1-phenyl-(914654-71-0)
• EPA Substance Registry System: Hydrazine, 1-(3-fluorophenyl)-1-phenyl-(914654-71-0)

Safety Data

• Hazardous Substances Data: 914654-71-0(Hazardous Substances Data)

Upstream product

• 640-60-8 toluene-4-sulfonic acid phenyl ester 
• 2924-16-5 3-fluorophenylhydrazine hydrochloride 
• 42116-43-8 tert-butyl 2-phenylhydrazine-1-carboxylate 
• 92491-22-0 tert-butyl 2-phenyldiazene-1-carboxylate 
• 1338369-67-7 N-tert-butoxycarbonyl-N'-(3-fluorophenyl)-N'-phenylhydrazine 
• 1073-06-9 3-fluorobromobenzene 
• 100-63-0 phenylhydrazine 

Downstream Products

• 500-41-4 3-fluoro-N-phenyl-aniline 

Relevant articles and documents

Palladium-catalyzed monoarylation of arylhydrazines with aryl tosylates

A palladium-catalyzed C-N bond coupling reaction between arylhydrazines and aryl tosylates for facile synthesis of unsymmetrical N,N-diarylhydrazines has been developed. Employing the catalyst system of Pd(TFA)2 associated with newly developed phosphine ligand L1, the monoarylation of arylhydrazine proceeds smoothly to afford desired products in good-to-excellent yields (up to 95%) with good functional group compatibility. This method provides an alternative synthetic pathway for accessing structurally diversified N,N-diarylhydrazines from simple and easily accessible coupling components.

Quinoline derivatives as neurokinin receptor antagonists

The present invention relates to substituted quinoline hydrazides of Formula (I): wherein R1, R2, R3, R4, R5, X, Y and Z are defined herein, pharmaceutical compositions comprising them and their use in treating diseases mediated by neurokinin-2 and/or neurokinin-3 (NK-3) receptors. These compounds can thus be used in methods of treatment to suppress and treat such disorders.