915948-92-4

Basic information

• Product Name: 5-Bromo-N,N-dimethylpyrimidine-2-carboxamide
• Synonyms: 5-Bromo-N,N-dimethylpyrimidine-2-carboxamide;2-Pyrimidinecarboxamide, 5-bromo-N,N-dimethyl-;EOS-61372
• CAS NO: 915948-92-4
• Molecular Formula: C₇H₈BrN₃O
• Molecular Weight: 230.07
• Mol File: 915948-92-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-Bromo-N,N-dimethylpyrimidine-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-N,N-dimethylpyrimidine-2-carboxamide(915948-92-4)
• EPA Substance Registry System: 5-Bromo-N,N-dimethylpyrimidine-2-carboxamide(915948-92-4)

Safety Data

• Hazardous Substances Data: 915948-92-4(Hazardous Substances Data)

Upstream product

• 1013335-78-8 5-bromopyridine-2-carboxylic acid chloride 
• 124-40-3 dimethyl amine 
• 37131-87-6 5-bromo-2-pyrimidinecarboxylic acid 

Downstream Products

• 1352570-07-0 5-(3-isopropoxy-5-(6-oxo-1,6-dihydropyrimidin-2-yl)phenoxy)-N,N-dimethylpyrimidine-2-carboxamide 
• 1448788-58-6 C₂₂H₂₂N₆O₅ 
• 1352570-41-2 (S)-5-(3-(1-hydroxypropan-2-yloxy)-5-(6-oxo-1,6-dihydropyrimidin-2-yl)phenoxy)-N,N-dimethylpyrimidine-2-carboxamide 
• 1352570-68-3 N,N-dimethyl-5-(3-(6-oxo-1,6-dihydropyrimidin-2-yl)-5-(pentan-3-yloxy)phenoxy)pyrimidine-2-carboxamide 
• 1352570-55-8 5-(3-(cyclopentyloxy)-5-(6-oxo-1,6-dihydropyrimidin-2-yl)phenoxy)-N,N-dimethylpyrimidine-2-carboxamide 
• 1352570-65-0 (S)-5-(3-(1-methoxypropan-2-yloxy)-5-(6-oxo-1,6-dihydropyrimidin-2-yl)phenoxy)-N,N-dimethylpyrimidine-2-carboxamide 
• 1352570-59-2 N,N-dimethyl-5-(3-(6-oxo-1,6-dihydropyrimidin-2-yl)-5-(tetrahydrofuran-3-yloxy)phenoxy)pyrimidine-2-carboxamide 

Relevant articles and documents

2-(3,5-DISUBSTITUTEDPHENYL)PYRIMIDIN-4(3H)-ONE DERIVATIVES

O N NH R3 R2 O R1 168 ABSTRACT The present invention provides a 2-(3,5-disubstitutedphenyl)pyrimidin- 4(3H)-one compound of Formula (I) 5 (I) or a pharmaceutically acceptable salt thereof wherein R 1, R2 and R3 are as defined herein. The compounds of Formula (I) have been found to act as glucokinase activators. Consequently, the compounds of Formula (I) and 10 the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucokinase.

SUBSTITUTED INDAZOLE AMIDES AND THEIR USE AS GLUCOKINASE ACTIVATORS

The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R4, R6, X, Y and Z are as defined herein. The compounds of Formula (I) have been found to act as glucokinase activators. Consequently, the compounds of Formula (I) and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucokinase.