916069-03-9Relevant articles and documents
Regioselective Synthesis of a C-4′′ Carbamate, C-6′′ n-Pr Substituted Cyclitol Analogue of SL0101
Fukuda, Shinji,Lannigan, Deborah A.,Li, Mingzong,Li, Yu,O'Doherty, George A.,Sandusky, Zachary M.,Vemula, Rajender,Wu, Bulan,Zhang, Qi
, p. 1448 - 1452 (2020/03/13)
An asymmetric synthesis of two analogues of SL0101 (1) has been achieved. The effort is aimed at the discovery of inhibitors of the p90 ribosomal S6 kinase (RSK) with improved bioavailability. The route relies upon the use of the Taylor catalyst to regios