919286-15-0Relevant articles and documents
Dialkylamino-2,4-dihydroxybenzoic acids as easily synthesized analogues of platensimycin and platencin with comparable antibacterial properties
Wang, Jingxin,Sintim, Herman O.
supporting information; scheme or table, p. 3352 - 3357 (2011/05/02)
Function matters more than synthesis: Simple analogues of platensimycin, nanomolar inhibitors of bacterial FabF enzymes, are made in just two-flask reactions from commercially available aldehydes. These readily synthesized analogues are as effective as pl
Total synthesis of platensimycin
Nicolaou,Li, Ang,Edmonds, David J.
, p. 7086 - 7090 (2007/10/03)
(Chemical Equation Presented) Beat the superbugs: The newly discovered antibiotic platensimycin (1) promises to combat current drug-resistant infections. The natural product shows potent activity against Gram-positive bacteria and contains a novel molecul