919787-23-8Relevant articles and documents
Diels-Alder Cycloaddition of Azepino[4,5-b]indoles Towards Hydrocarbazole Derivatives and Related Heterocycles
Xie, Fukai,Li, Xiang,Xu, Liangyu,Ma, Jun,Sun, Lei,Zhang, Bo,Lin, Bin,Cheng, Maosheng,Liu, Yongxiang
, p. 873 - 889 (2022/01/26)
An approach to hydrocarbazoles bearing an all-carbon quaternary center at C4a position was developed via a Br?nsted acid-initiated Diels-Alder cycloaddition/retro-aza-Michael addition cascade process from azepino[4,5-b]indoles and commercially available d
Gold-Catalyzed Intramolecular Tandem Cyclization of Indole-Ynamides: Diastereoselective Synthesis of Spirocyclic Pyrrolidinoindolines
Zheng, Nan,Chang, Yuan-Yuan,Zhang, Li-Jie,Gong, Jian-Xian,Yang, Zhen
, p. 371 - 375 (2016/05/19)
A gold-catalyzed intramolecular tandem cyclization of indole-ynamide affords tetracyclic spirocyclic pyrrolidinoindoline bearing an all-carbon quaternary stereocentre in a single step; however, when the reaction was carried out in the presence of BF3·Et2O, the corresponding tricyclic spirocyclic pyrrolidinoindoline-based enones are produced through a key 1,5-hydride shift. The developed chemistry provides a diastereoselective and straightforward entry to structurally diverse polycylic pyrrolidinoindolines from indole-ynamides in one-pot reactions under mild conditions.
