92127-20-3

Basic information

• Product Name: 4-Piperidinecarbonyl chloride, 1-benzoyl-3-ethenyl-, cis-
• CAS NO: 92127-20-3
• Molecular Formula: C15H16ClNO2
• Molecular Weight: 277.751
• Mol File: 92127-20-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-Piperidinecarbonyl chloride, 1-benzoyl-3-ethenyl-, cis-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinecarbonyl chloride, 1-benzoyl-3-ethenyl-, cis-(92127-20-3)
• EPA Substance Registry System: 4-Piperidinecarbonyl chloride, 1-benzoyl-3-ethenyl-, cis-(92127-20-3)

Safety Data

• Hazardous Substances Data: 92127-20-3(Hazardous Substances Data)

Upstream product

• 106542-21-6 4-butenoic acid 
• 92127-16-7 C₂₁H₃₁NO₃Si 
• 106542-22-7 4-butenoic acid lactone 
• 92127-14-5 4-butenoic acid 
• 35340-63-7 3-benzoylaminobutanoic acid 
• 92127-17-8 (+/-)-cis-N-benzoyl-3-ethenyl-4-piperidinecarboxylic acid 

Downstream Products

• 26013-17-2 (+/-)-N-benzoylmeroquinene methyl ester 
• 92127-18-9 1-((3S,4S)-1-Benzoyl-3-vinyl-piperidin-4-yl)-2-diazo-ethanone 

Relevant articles and documents

CLAISEN-REARRANGEMENT-MEDIATED RING CONTRACTION OF MACROCYCLIC LACTONES A NEW APPROACH TO CARBOCYCLES AND HETEROCYCLES

Macrocyclic ketene acetals 3 undergo Claisen rearrangements smoothly and constitute a viable and general approach to hetero- or carbocyclic ring systems 4.This novel ring contraction process is subject to high internal asymmetric induction (cf. lactones 7 -> carbocycles 8) as well as relative asymmetric induction in the rearrangements of ketene acetals derived from lactones 18, 23 and 27.Finally, N-benzoylmeroquinene methyl ester (37) was prepared to demonstrate the potential of this methodology in heterocycle synthesis.