92161-65-4

Basic information

• Product Name: methyl 2-(4-chloro-2-nitrophenylthio)benzoate
• Synonyms: methyl 2-(4-chloro-2-nitrophenylthio)benzoate;2-[(4-chloro-2-nitrophenyl)thio]benzoic acid methyl ester;2-[(4-chloro-2-nitro-phenyl)thio]benzoic acid methyl ester;methyl 2-(4-chloro-2-nitrophenyl)sulfanylbenzoate;methyl 2-(4-chloro-2-nitro-phenyl)sulfanylbenzoate;MFCD08582838
• CAS NO: 92161-65-4
• Molecular Formula: C₁₄H₁₀ClNO₄S
• Molecular Weight: 323.76
• Mol File: 92161-65-4.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 2-(4-chloro-2-nitrophenylthio)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(4-chloro-2-nitrophenylthio)benzoate(92161-65-4)
• EPA Substance Registry System: methyl 2-(4-chloro-2-nitrophenylthio)benzoate(92161-65-4)

Safety Data

• Hazardous Substances Data: 92161-65-4(Hazardous Substances Data)

Usage

Uses

Methyl 2-((4-chloro-2-nitrophenyl)thio)benzoate is a useful intermediate for organic synthesis.

Upstream product

• 345-18-6 2-fluoro-5-chloronitrobenzene 
• 4892-02-8 Methyl thiosalicylate 
• 700-37-8 4-chloro-2-fluoro-nitrobenzene 
• 60-29-7 diethyl ether 
• 17999-25-6 methyl thiosalicylate 
• 89-61-2 2,5-dichloronitrobenzene 

Downstream Products

• 93535-13-8 2-(2-amino-4-chloro-phenylsulfanyl)-benzoic acid methyl ester 
• 126395-03-7 2-(4-chloro-2-nitrophenylsulfanyl)benzoic acid 
• 3158-80-3 8-chloro-10H-dibenzo[b,f][1,4]thiazepin-11-one 
• 167996-98-7 2-(2-amino-4-chlorophenylsulfanyl)benzoic acid 
• 1071718-24-5 methyl 2-((2-amino-4-chlorophenyl)thio)benzoate hydrochloride salt 
• 1451261-79-2 2-({2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorophenyl}sulfanyl)benzoic acid 

Relevant articles and documents

BENZOFURAN-2-SULFONAMIDES DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS

The present invention relates to novel benzofuran-2-sulfonamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors.

IRON CATALYZED CROSS-COUPLING REACTIONS OF IMIDOYL DERIVATIVES

Disclosed is a process for preparing a compound of formula A - N=C(D)(B), from a compound of formula A-N=C(E)(B) and a compound of formula D-M using an iron catalyst, where the process has is represented by Equation (I).

USE OF N-DESMETHYLCLOZAPINE AND RELATED COMPOUNDS AS DOPAMINE STABILIZING AGENTS

Disclosed herein is the use of N-desmethylclozapine (NDMC) and related compounds to treat a variety of neuropsychiatric diseases including psychosis. It is shown that NDMC and related compounds are agonists or partial agonists at D2 and D3 dopamine receptors and thus may be effective as a dopamine stabilizing agent, allowing it to be used to treat or provide reduced incidence of Extrapyramidal symptoms (EPS) and/or tardive dyskinesias (TD). Also disclosed is administering NDMC and related compounds in combination with other anti-psychotic agents.