92207-60-8Relevant articles and documents
2,2-DIFLUORO-3-HYDROXYESTERS BY REFORMATSKII REACTION
Hallinan, E. Ann,Fried, Josef
, p. 2301 - 2302 (1984)
Ethyl bromodifluoroacetate undergoes facile Reformatskii addition to aldehydes and ketones to form 2,2-difluoro-3-hydroxyesters.
Synthesis of Enantioenriched α,α-Difluoro-β-arylbutanoic Esters by Pd-Catalyzed Asymmetric Hydrogenation
Dong, Kaiwu,Feng, Sitian,Shen, Chaoren,Tang, Yitian,Yang, Chenjue
supporting information, p. 7508 - 7512 (2020/10/09)
Synthesis of optically active gem-difluorinated organic molecules attracts a great deal of interest due to their unique properties in pharmaceutical and agrochemical areas. Herein, a series of enantioenriched α,α-difluoro-β-arylbutanoic esters were prepar
Decarboxylative aldol reaction of α,α-difluoro-β-ketocarboxylate salt: A facile method for generation of difluoroenolate
Tarui, Atsushi,Oduti, Mayuna,Shinya, Susumu,Sato, Kazuyuki,Omote, Masaaki
, p. 20568 - 20575 (2018/06/14)
We developed a decarboxylative aldol reaction using α,α-difluoro-β-ketocarboxylate salt, carbonyl compounds, and ZnCl2/N,N,N′,N′-tetramethylethylenediamine. The generation of difluoroenolate proceeded smoothly under mild heating to provide α,α-
