92310-70-8

Basic information

• Product Name: Carbamic acid, dimethyl-, 4-formylphenyl ester
• CAS NO: 92310-70-8
• Molecular Formula: C10H11NO3
• Molecular Weight: 193.202
• Mol File: 92310-70-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Carbamic acid, dimethyl-, 4-formylphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, dimethyl-, 4-formylphenyl ester(92310-70-8)
• EPA Substance Registry System: Carbamic acid, dimethyl-, 4-formylphenyl ester(92310-70-8)

Safety Data

• Hazardous Substances Data: 92310-70-8(Hazardous Substances Data)

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 79-44-7 N,N-Dimethylcarbamoyl chloride 

Downstream Products

• 100-10-7 4-dimethylamino-benzaldehyde 
• 663180-14-1 dimethyl-carbamic acid 4-[1-(tert-butyl-dimethyl-silanyloxy)-3-(4-nitro-phenoxy)-propyl]-phenyl ester 
• 663179-23-5 3-(tert-butyl-dimethyl-silanyloxy)-3-(4-dimethylcarbamoyloxy-phenyl)-propionic acid ethyl ester 
• 663180-16-3 dimethyl-carbamic acid 4-[1-hydroxy-3-(4-nitro-phenoxy)-propyl]-phenyl ester 
• 578730-06-0 dimethylcarbamic acid 4-[1-bromo-3-(4-nitrophenoxy)propyl]phenyl ester 

Relevant articles and documents

Design, synthesis, biological evaluation, and molecular modeling studies of chalcone-rivastigmine hybrids as cholinesterase inhibitors

A series of novel chalcone-rivastigmine hybrids were designed, synthesized, and tested in vitro for their ability to inhibit human acetylcholinesterase and butyrylcholinesterase. Most of the target compounds showed hBChE selective activity in the micro- a

A molecular approach to rationally constructing specific fluorogenic substrates for the detection of acetylcholinesterase activity in live cells, mice brains and tissues

Acetylcholinesterase (AChE) is an extremely critical hydrolase tightly associated with neurological diseases. Currently, developing specific substrates for imaging AChE activity still remains a great challenge due to the interference from butyrylcholinesterase (BChE) and carboxylesterase (CE). Herein, we propose an approach to designing specific substrates for AChE detection by combining dimethylcarbamate choline with a self-immolative scaffold. The representative P10 can effectively eliminate the interference from CE and BChE. The high specificity of P10 has been proved via imaging AChE activity in cells. Moreover, P10 can also be used to successfully map AChE activity in different regions of a normal mouse brain, which may provide important data for AChE evaluation in clinical studies. Such a rational and effective approach can also provide a solid basis for designing probes with different properties to study AChE in biosystems and another way to design specific substrates for other enzymes. This journal is

A kind of carbamate-koncar ketone choline esterase inhibitor and its preparation method and application (by machine translation)

The present invention discloses a kind of carbamate-koncar ketone choline esterase inhibitor and its preparation method and application, belongs to the field of medicinal chemistry. Cholinesterase inhibitors of the invention represented by general formula