92433-38-0

Basic information

• Product Name: 1H-Indole, 5-chloro-1-(phenylmethyl)-
• Synonyms: 1-benzyl-5-chloro-1H-indole;N-benzyl-5-chloroindole;5-Chloro-1-benzylindole;5-chloro-1-benzyl-1H-indole
• CAS NO: 92433-38-0
• Molecular Formula: C15H12ClN
• Molecular Weight: 241.72
• Mol File: 92433-38-0.mol
• Article Data: 22

Chemical Properties

• Melting Point: 58-60 °C
• Boiling Point: 407.1±28.0 °C(Predicted)
• Density: 1.15±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 1H-Indole, 5-chloro-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 5-chloro-1-(phenylmethyl)-(92433-38-0)
• EPA Substance Registry System: 1H-Indole, 5-chloro-1-(phenylmethyl)-(92433-38-0)

Safety Data

• Hazardous Substances Data: 92433-38-0(Hazardous Substances Data)

Upstream product

• 17422-32-1 5-chloro-1H-indole 
• 100-39-0 benzyl bromide 
• 936840-09-4 benzyl(4-chloro-2-ethynylphenyl)amine 
• 2948-37-0 N-(4-chlorophenyl)benzylamine 
• 1429616-66-9 N-benzyl-4-chloro-N-(2,2-diethoxyethyl)aniline 
• 60085-59-8 C₁₂H₁₈ClNO₂ 
• 939-26-4 2-bromomethylnaphthyl bromide 
• 260783-80-0 N,N,N--trimethyl--1--phenylmethanaminium trifluoromethanesulfonate 

Downstream Products

• 227803-33-0 2-benzyl-5-chloro-1H-indole 
• 1220283-74-8 (+/-)-tert-butyl 2-[(1-benzyl-1H-indol-5-yl)methyl]pyrrolidine-1-carboxylate 
• 1310492-99-9 1-benzyl-3-(butylthio)-5-chloro-1H-indole 
• 1310492-95-5 1-benzyl-5-chloro-3-(phenylthio)-1H-indole 
• 1316844-52-6 1-benzyl-5-chloro-1H-indol-3-yl acetate 
• 1395104-04-7 1-benzyl-5-chloro-1H-3-iodoindole 
• 16382-21-1 1-benzyl-5-methoxyindole 
• 3377-71-7 N-benzylindole 
• 1426847-72-4 1-benzyl-5-chloro-1H-indole-3-carbonitrile 
• 1206163-56-5 1-benzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole 

Relevant articles and documents

Transition-Metal-Free and Base-Promoted Carbon-Heteroatom Bond Formation via C-N Cleavage of Benzyl Ammonium Salts

A facile and general method for constructing carbon-heteroatom (C-P, C-O, C-S, and C-N) bonds via C-N cleavage of benzyl ammonium salts under transition-metal-free conditions was reported. The combination of t-BuOK and 18-crown-6 enabled a wide range of substituted benzyl ammonium salts to couple readily with different kinds of heteroatom nucleophiles, i.e. hydrogen phosphoryl compounds, alcohols, thiols, and amines. Good functional group tolerance was demonstrated. The scale-up reaction and one-pot synthesis were also successfully performed.

The palladium-catalyzed direct C3-cyanation of indoles using acetonitrile as the cyanide source

The ligand-free palladium-catalyzed C3-cyanation of indoles via direct C-H functionalization was achieved. This protocol, utilizing CH3CN as a green and readily available cyanide source, produced the desired products in moderate to good yields through transition-metal-catalyzed C-CN bond cleavage. This journal is

Design and synthesis of multipotent 3-aminomethylindoles and 7-azaindoles with enhanced protein phosphatase 2A-activating profile and neuroprotection

We report the synthesis and pharmacological evaluation of new 3-aminomethylindoles derivatives with neuroprotective properties designed to present multi-target activity centered on reducing the neuronal Ca2+ overload and preventing phosphatase