92741-82-7

Basic information

• Product Name: Propanedioic acid, (2,4-dimethoxyphenyl)-, diethyl ester
• CAS NO: 92741-82-7
• Molecular Formula: C15H20O6
• Molecular Weight: 296.32
• Mol File: 92741-82-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, (2,4-dimethoxyphenyl)-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, (2,4-dimethoxyphenyl)-, diethyl ester(92741-82-7)
• EPA Substance Registry System: Propanedioic acid, (2,4-dimethoxyphenyl)-, diethyl ester(92741-82-7)

Safety Data

• Hazardous Substances Data: 92741-82-7(Hazardous Substances Data)

Upstream product

• 20469-63-0 1-iodo-2,4-dimethoxybenzene 
• 105-53-3 diethyl malonate 
• 17715-69-4 1-Bromo-2,4-dimethoxybenzene 
• 92741-81-6 ethyl (2,4-dimethoxyphenyl)acetate 

Downstream Products

• 35618-98-5 3-(2,4-dimethoxy-phenyl)-4-hydroxy-8,9-dimethyl-7H-pyrano[2,3-e]indol-2-one 
• 59870-68-7 (±)-glabridin 
• 59870-68-7 glabridin 

Relevant articles and documents

The synthesis of benzofuroquinolines. III. Two dihydroxybenzofuroquinolinones

-

Method for synthesizing optically pure glabridin

The invention relates to a method for synthesizing optically pure glabridin. According to the method, chiral carbon of optically pure glabridin is constructed through biological enzyme catalysis, optically pure glabridin is prepared in combination with an organic synthesis method, and the key steps are that a chiral intermediate compound III is generated by using a lipase catalysis compound II, and an important intermediate compound IV is obtained through a bromination reaction. According to the method for synthesizing optically pure glabridin, raw materials are cheap and easy to obtain, and the total yield is high.

Room-temperature copper-catalyzed α-arylation of malonates

An effective method in targeting α-aryl malonates is reported. In the presence of a catalytic amount of 2-picolinic acid and Cul, the coupling of aryl iodides with diethyl malonate proceeds smoothly even at room temperature. The high levels of functional group compatibility and exceptionally mild reaction conditions offer this an attractive protocol in accessing a variety of arylated malonates.