93349-99-6

Basic information

• Product Name: 5-Bromo-6-methoxynicotinic acid methyl ester
• Synonyms: 5-Bromo-6-methoxynicotinic acid methyl ester;Methyl 5-Bromo-6-methoxynicotinate;5-Bromo-6-methoxynicotinic acid methyl este
• CAS NO: 93349-99-6
• Molecular Formula: C₈H₈BrNO₃
• Molecular Weight: 246.05802
• Mol File: 93349-99-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 275℃
• Flash Point: 120℃
• Appearance: /
• Density: 1.53
• Vapor Pressure: 0.00529mmHg at 25°C
• Refractive Index: 1.54
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: -0.99±0.20(Predicted)
• CAS DataBase Reference: 5-Bromo-6-methoxynicotinic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-6-methoxynicotinic acid methyl ester(93349-99-6)
• EPA Substance Registry System: 5-Bromo-6-methoxynicotinic acid methyl ester(93349-99-6)

Safety Data

• Hazardous Substances Data: 93349-99-6(Hazardous Substances Data)

Usage

General Description

5-Bromo-6-methoxynicotinic acid methyl ester is a chemical compound with the molecular formula C9H9BrNO3. It is a derivative of nicotinic acid and is often used in the pharmaceutical industry as a building block for the synthesis of various drugs and biologically active molecules. 5-Bromo-6-methoxynicotinic acid methyl ester is commonly used in organic synthesis and medicinal chemistry due to its ability to undergo various chemical reactions to produce novel compounds with potential therapeutic properties. Additionally, it is a valuable research tool for the development of new drugs and pharmaceuticals due to its unique chemical structure and reactivity.

InChI:InChI=1/C8H8BrNO3/c1-12-7-6(9)3-5(4-10-7)8(11)13-2/h3-4H,1-2H3

Upstream product

• 124-41-4 sodium methylate 
• 78686-77-8 5-bromo-6-chloro-3-pyridinecarboxylic acid methyl ester 
• 5006-66-6 6-hydroxynicotinic acid 
• 1190862-68-0 ethyl 5,6-dibromonicotinate 
• 5006-66-6 6-hydroxy-3-pyridinecarboxylic acid 
• 41668-13-7 5-bromo-6-hydroxy-3-pyridinecarboxylic acid 
• 381247-99-0 methyl 5-bromo-6-hydroxypyridine-3-carboxylate 
• 29241-62-1 5-bromo-6-chloronicotinic acid 
• 381247-99-0 methyl 5-bromo-6-oxo-1,6-dihydropyridine-3-carboxylate 

Downstream Products

• 93350-05-1 Methyl 5-(2-Methoxyphenyl)-6-methoxynicotinate 
• 93350-03-9 Methyl 5-Phenyl-6-methoxynicotinate 
• 1186194-46-6 5-bromo-6-methoxypyridine-3-carboxylic acid 
• 1298046-50-0 1-{[5-(3-cyano-phenyl)-6-methoxy-pyridine-3-carbonyl]-amino}-cycloheptanecarboxylic acid methyl ester 
• 1219936-55-6 (5-bromo-6-methoxypyridin-3-yl)methanol 
• 1402799-14-7 C₂₁H₂₉NO₄ 
• 234107-97-2 methyl 6-methoxy-5-methylnicotinate 

Relevant articles and documents

PYRAZOLYL-SUBSTITUTED PYRIDONE COMPOUNDS AS SERINE PROTEASE INHIBITORS

There are provided inter alia pyrazolyl-substituted pyridone compounds, which exhibit biological activity, e.g., inhibitory action, against serine proteases, including thrombin and various kallikreins. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of serine proteases, including thrombin and various kallikreins.

AROMATIC RING COMPOUND

Provided is an aromatic ring compound having a GPR40 agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof has a GPR40 agonist activity, and is useful as an agent for the prophylaxis or treatment of diabetes and the like.

SUBSTITUTED PYRIDINE COMPOUNDS AS CRAC MODULATORS

The present invention relates to compounds described herein Formula (I) and pharmaceutical acceptable salts thereof, which modulate the activity of calcium release- activated calcium (CRAC) channel. The invention also describes the compounds of Formula (I)and pharmaceutical compositions containing such compounds thereof for treating, managing, and/or lessening the severity of diseases, disorders, syndromes or conditions associated with the modulation of calcium release-activated calcium (CRAC) channel.