934006-98-1Relevant articles and documents
Design and synthesis of new potent dipeptidyl peptidase IV inhibitors with enhanced ex vivo duration
Kondo, Takashi,Nekado, Takahiro,Sugimoto, Isamu,Ochi, Kenya,Takai, Shigeyuki,Kinoshita, Atsushi,Tajima, Yohei,Yamamoto, Susumu,Kawabata, Kazuhito,Nakai, Hisao,Toda, Masaaki
, p. 2631 - 2650 (2007)
A series of 5β-methylprolyl-2-cyanopyrrolidine analogs were synthesized and evaluated as DPP-IV inhibitors, and the duration of their ex vivo activity was assessed. Comparison of their potency and duration of action was done among three different species.