934472-39-6

Basic information

• Product Name: C₁₄H₁₉NO₃S
• Synonyms: C₁₄H₁₉NO₃S
• CAS NO: 934472-39-6
• Molecular Weight: 281.376
• Mol File: 934472-39-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₉NO₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₉NO₃S(934472-39-6)
• EPA Substance Registry System: C₁₄H₁₉NO₃S(934472-39-6)

Safety Data

• Hazardous Substances Data: 934472-39-6(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 81097-32-7 N-hex-5-enyl(4-methylphenyl)sulfonamide 
• 1088669-95-7 C₁₄H₁₉NO₃S 
• 616866-44-5 (2R)-N-(p-toluenesulfonyl)-aspartic acid dimethyl ester 
• 934472-37-4 2-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-1-(toluene-4-sulfonyl)-piperidine 
• 934472-38-5 (S)-N-tosyl-2-piperidinylethanol 

Downstream Products

• 1227006-30-5 2-[(1,3-dioxolan-2-yl)methyl]-1-tosylpiperidine 
• 1227006-31-6 2-hydroxyethyl 2-(1-tosylpiperidin-2-yl)ethanoate 
• 251995-67-2 (-)-benzyl (S)-2-[(R)-2-hydroxypropyl]piperidine-1-carboxylate 
• 251995-64-9 (-)-benzyl (S)-2-[(S)-2-hydroxypropyl]piperidine-1-carboxylate 
• 1415-36-7 (-)-norsedamine 
• 495-47-6 1-phenyl-2-[(2S)-piperidin-2-yl]-(1R)-ethan-1-ol 
• 497-89-2 2-[1-methyl-(2S)-piperidin-2-yl]-1-phenyl-(1R)-ethan-1-ol 
• 497-88-1 (-)-sedamine 
• 507454-03-7 (+)-(2R)-3-[(2S)-N-(p-toluenesulfonyl)piperidin-2-yl]propan-2-ol 
• 186891-49-6 (+)-(2S)-3-[(2S)-N-(p-toluenesulfonyl)piperidin-2-yl]propan-2-ol 
• 934472-53-4 4-nitro-benzoic acid 1-phenyl-2-[1-(toluene-4-sulfonyl)-piperidin-2-yl]-ethyl ester 
• 934472-57-8 4-nitro-benzoic acid 1-phenyl-2-[1-(toluene-4-sulfonyl)-piperidin-2-yl]-ethyl ester 
• 934472-58-9 4-nitro-benzoic acid 1-methyl-2-[1-(toluene-4-sulfonyl)-piperidin-2-yl]-ethyl ester 
• 934472-54-5 4-nitro-benzoic acid 1-methyl-2-[1-(toluene-4-sulfonyl)-piperidin-2-yl]-ethyl ester 

Relevant articles and documents

Development of oxidative formylation and ketonylation reactions

The first oxidative formylation and oxidative ketonylation of alkenylamines and alkenyl alcohols is demonstrated. A range of substrates that participate in this process are provided. Oxidative formylation was found to proceed optimally with the use of triphenylsilane as the hydride source. Oxidative ketonylation was feasible with a number of organometallic partners, especially dialkylzinc or organostannanes. An interesting finding regarding the fate of various acylpalladium intermediates is discussed. Georg Thieme Verlag Stuttgart.

An efficient approach to 2-substituted N-tosylpiperdines: asymmetric synthesis of 2-(2-hydroxy substituted)piperidine alkaloids

We have developed an efficient and a general approach to chiral 2-substituted N-tosylpiperidines starting from chiral α-substituted-N-tosylaziridines. Using this approach, we have synthesized (+)-coniine. The synthesis of chiral N-tosyl-2-piperidinylethanol 15 and ent-15, was achieved from l- and d-aspartic acids, respectively in few steps. Piperidine 15 was converted into 2-(2-hydroxysubstituted)piperidines of type 2 in optically active form. By applying this strategy, asymmetric syntheses of halosaline (R,R)-2a, (+)- and (-)-sedamine 2b, (+)- and (-)-allosedamine 2c, (+)- and (-)-sedridine 2d, (+)- and (-)-allosedridine 2e, (+)-tetraponerine T-3 3a, T-4 3c, T-7 3b, and T-8 3d have been achieved in high yields. These stereoisomers can be interconverted via Mitsunobu inversion in excellent yields.