93546-63-5

Basic information

• Product Name: N-{Imino-[3-(5-p-tolyl-[1,3,4]oxadiazol-2-yl)-ureido]-methyl}-4-methyl-piperazine-1-carboxamidine
• CAS NO: 93546-63-5
• Molecular Weight: 385.429
• Mol File: 93546-63-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-{Imino-[3-(5-p-tolyl-[1,3,4]oxadiazol-2-yl)-ureido]-methyl}-4-methyl-piperazine-1-carboxamidine(CAS DataBase Reference)
• NIST Chemistry Reference: N-{Imino-[3-(5-p-tolyl-[1,3,4]oxadiazol-2-yl)-ureido]-methyl}-4-methyl-piperazine-1-carboxamidine(93546-63-5)
• EPA Substance Registry System: N-{Imino-[3-(5-p-tolyl-[1,3,4]oxadiazol-2-yl)-ureido]-methyl}-4-methyl-piperazine-1-carboxamidine(93546-63-5)

Safety Data

• Hazardous Substances Data: 93546-63-5(Hazardous Substances Data)

Upstream product

• 34352-59-5 1-methylpiperazine hydrochloride 
• 93546-48-6 N⁵-(ethoxycarbonyl)-4-methyl-1-piperazinobiguanide 
• 33621-60-2 2-amino-5-(4-methylphenyl)-1,3,4-oxadiazole 
• 5900-60-7 4-methyl-1-piperazinobiguanide hydrochloride 

Relevant articles and documents

Synthesis of 4-Methyl-1-piperazino/piperidinobiguanidines as Oral Hypoglycemic Agents

A series of N5-(4-aryl-5-arylazothiazol-2-yl- or 5-aryl-1,3,4-oxadiazol-2-yl-aminocarbonyl)-4-methyl-1-piperazino/piperidino-biguanidines (III-l and IVa-j) have been synthesised from N5-ethoxycarbonyl-4-methyl-1-piperazino/piperidino-biguanidines (IIa,b).The latter compounds in turn have been prepared by the reaction of N1-substituted biguanide hydrochlorides (Ia,b) with ethyl chloroformate.A few compounds of the series, when administered orally in rats, cause reduction in the blood sugar to a significant extent but most of these have been found to be toxic.