937021-95-9Relevant articles and documents
A short and scalable route to orthogonally O-protected 2-deoxystreptamine
Van Den Broek, Sebastiaan A. M. W.,Gruijters, Bas W. T.,Rutjes, Floris P. J. T.,Van Delft, Floris L.,Blaauw, Richard H.
, p. 3577 - 3580 (2007)
(Chemical Equation Presented) A seven-step synthesis of orthogonally O-protected 2-deoxy-streptamine has been developed from readily available neomycin, with an overall yield of 28%. Key chemical transformations include a chemoselective glycosidic bond hy
Investigation of the regioselectivity for the Staudinger reaction and its application for the synthesis of aminoglycosides with N-1 modification
Li, Jie,Chiang, Fang-I.,Chen, Hsiao-Nung,Chang, Cheng-Wei Tom
, p. 4055 - 4066 (2008/02/04)
(Chemical Equation Presented) The criteria for controlling the regioselectivity of Staudinger reduction of azides have been investigated. These findings enable a convenient direct N-1 modification of the perazidoneamine and perazidoribostamycin resulting