93703-48-1 Usage
Description
3,3',4,4'-Tetrabromodiphenyl ether, also known as BDE-77, is a flame retardant chemical that belongs to the group of polybrominated diphenyl ethers (PBDEs). It is commonly used in various consumer products such as electronics, furniture, and textiles. However, it is known to persist in the environment and bioaccumulate in living organisms, posing potential toxic effects on the environment and human health, including impacts on the endocrine, reproductive, and nervous systems.
Uses
Used in Electronics Industry:
3,3',4,4'-Tetrabromodiphenyl ether is used as a flame retardant in electronic devices to reduce the risk of fire and improve safety.
Used in Furniture Industry:
In the furniture industry, BDE-77 is used as a flame retardant in materials such as upholstery and foam to meet safety standards and reduce the risk of fire.
Used in Textile Industry:
3,3',4,4'-Tetrabromodiphenyl ether is used in textiles to provide flame resistance, making them suitable for use in applications such as children's sleepwear and other products that require fire safety.
Despite its widespread use, the use of BDE-77 has been restricted or banned in many countries due to its potential toxic effects on the environment and human health. It is essential to manage and dispose of products containing BDE-77 properly to minimize the risk it poses.
Check Digit Verification of cas no
The CAS Registry Mumber 93703-48-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,7,0 and 3 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 93703-48:
(7*9)+(6*3)+(5*7)+(4*0)+(3*3)+(2*4)+(1*8)=141
141 % 10 = 1
So 93703-48-1 is a valid CAS Registry Number.
93703-48-1Relevant articles and documents
Synthesis of polybrominated diphenyl ethers and their capacity to induce CYP1A by the Ah receptor mediated pathway
Chen,Konstantinov,Chittim,Joyce,Bols,Bunce
, p. 3749 - 3756 (2007/10/03)
Polybrominated diphenyl ethers (PBDEs) have become widely distributed as environmental contaminants due to their use as flame retardants. Their structural similarity to other halogenated aromatic pollutants has led to speculation that they might share toxicological properties such as hepatic enzyme induction. In this work we synthesized a number of PBDE congeners, studied their affinity for rat hepatic Ah receptor through competitive binding assays, and determined their ability to induce hepatic cytochrome P-450 enzymes by means of EROD (ethoxyre-sorufin-O-deethylase) assays in human, rat, chick, and rainbow trout cells. Both pure PBDE congeners and commercial PBDE mixtures had Ah receptor binding affinities 10-2-10-5 times that of 2,3,7,8-tetrachlorodibenzo-p-dioxin. In contrast with polychlorinated biphenyls, Ah receptor binding affinities of PBDEs could not be related to the planarity of the molecule, possibly because the large size of the bromine atoms expands the Ah receptor's binding site. EROD activities of the PBDE congeners followed a similar rank order in all cells. Some congeners, notably PBDE 85, did not follow the usual trend in which strength of Ah receptor binding affinity paralleled P-450 induction potency. Use of the gel retardation assay with a synthetic oligonucleotide indicated that in these cases the liganded Ah receptor failed to bind to the DNA recognition sequence.
BROMINATION OF TRIPHENYLOXONIUM CATIONS
Tolstaya, T. P.,Vanchikova, L. N.,Lisichkina, I. N.
, p. 1282 - 1285 (2007/10/02)
-
