938435-69-9 Usage
Description
AV-45, also known as 4-[(1E)-2-[6-[2-[2-(2-Fluoroethoxy)ethoxy]ethoxy]-3-pyridinyl]ethenyl]-N-methyl-benzenamine, is a chemical compound that has been studied for its potential applications in various fields, including neuroscience and drug metabolism.
Uses
Used in Neuroscience Research:
AV-45 is used as a PET (positron emission tomography) imaging agent for studying the brain's uptake of PET agents. This helps researchers to better understand the distribution and metabolism of these agents in the brain, which can be crucial for developing new treatments for neurological disorders.
Used in Drug Metabolism Studies:
In the field of drug metabolism, AV-45 is used in chemometric studies to investigate its behavior in rat plasma and liver microsomes. This research can provide valuable insights into the compound's metabolic pathways and potential interactions with other drugs or substances, ultimately contributing to the development of safer and more effective medications.
Check Digit Verification of cas no
The CAS Registry Mumber 938435-69-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,8,4,3 and 5 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 938435-69:
(8*9)+(7*3)+(6*8)+(5*4)+(4*3)+(3*5)+(2*6)+(1*9)=209
209 % 10 = 9
So 938435-69-9 is a valid CAS Registry Number.
938435-69-9Relevant articles and documents
Facile synthesis of TEG-substituted 4-(N-methyl-N-Boc-amino)styrylpyridine and PET imaging agent [F]florbetapir ([F]AV-45)
Yao, Tuo,Li, Zhi
supporting information, p. 422 - 427 (2018/02/06)
Triethylene glycol-substituted 4-(N-methyl-N-Boc-amino)styrylpyridine which can serve as key precursor for many monodentate and multidentate imaging agents for Aβ plaques in human brain has been readily synthesized with cost-effective starting materials. The important non-radioactive monodentate positron emission tomography agent [F]florbetapir ([F]AV-45) has also been prepared by our new method.
