17211-08-4

Basic information

• Product Name: DIMETHYL(4-BROMOBENZYL)PHOSPHONATE
• Synonyms: DIMETHYL(4-BROMOBENZYL)PHOSPHONATE;Dimethyl(4-bromobenzyl)phosphonate, 97 % min.
• CAS NO: 17211-08-4
• Molecular Formula: C₉H₁₂BrO₃P
• Molecular Weight: 279.07
• Mol File: 17211-08-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: DIMETHYL(4-BROMOBENZYL)PHOSPHONATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL(4-BROMOBENZYL)PHOSPHONATE(17211-08-4)
• EPA Substance Registry System: DIMETHYL(4-BROMOBENZYL)PHOSPHONATE(17211-08-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 17211-08-4(Hazardous Substances Data)

Usage

General Description

DIMETHYL(4-BROMOBENZYL)PHOSPHONATE is a chemical compound with the molecular formula C9H12BrO3P. It is a phosphonate ester that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The compound is a clear, colorless liquid with a faint, sweet odor. It is primarily used in organic synthesis as a reagent for the preparation of various organic compounds. DIMETHYL(4-BROMOBENZYL)PHOSPHONATE is considered to have low toxicity and is stable under normal conditions, making it a useful compound in chemical research and manufacturing processes.

Upstream product

• 589-15-1 1-bromomethyl-4-bromobenzene 
• 121-45-9 phosphorous acid trimethyl ester 
• 868-85-9 Dimethyl phosphite 
• 512-56-1 trimethyl phosphite 
• 122-52-1 triethyl phosphite 

Downstream Products

• 851636-85-6 (5E,7E)-8-((4'-bromophenyl)octa-5,7-dienyloxyl)-(tert-butyl)dimethylsilane 
• 851636-87-8 (5E,7E)-8-(4'-bromophenyl)octa-5,7-dienal 
• 851636-86-7 (5E,7E)-8-(4'bromophenyl)octa-5,7-dien-1-ol 
• 851636-88-9 dimethyl (6E,8E)-9-(4'-bromophenyl)-2-hydroxynona-6,8-dienylphosphonate 
• 851636-89-0 dimethyl (6E,8E)-9-(4'-bromophenyl)-2-oxonona-6,8-dienylphosphonate 
• 851636-90-3 (3E,9E,11E)-1-azido-12-(4'-bromophenyl)dodeca-3,9,11-triene-5-one 
• 959427-94-2 4-[2,2-bis(4-cyanophenyl)ethenyl]bromobenzene 
• 18648-66-3 1-bromo-4-(2,2-diphenylvinyl)benzene 
• 1269206-17-8 1-[4-(2,2-diphenylvinyl)phenyl]pyrene 
• 288105-04-4 1,1-diphenyl-2-(4-dihydroxyboronphenyl)-ethene 
• 57438-81-0 1-(4-bromophenyl)-2-(1-naphthyl)ethylene 
• 4714-24-3 1-bromo-4-styrylbenzene 
• 938435-69-9 (E)-4-(2-(6-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)pyridin-3-yl)vinyl)-N-methyl benzenamine 

Relevant articles and documents

Facile synthesis of TEG-substituted 4-(N-methyl-N-Boc-amino)styrylpyridine and PET imaging agent [F]florbetapir ([F]AV-45)

Triethylene glycol-substituted 4-(N-methyl-N-Boc-amino)styrylpyridine which can serve as key precursor for many monodentate and multidentate imaging agents for Aβ plaques in human brain has been readily synthesized with cost-effective starting materials. The important non-radioactive monodentate positron emission tomography agent [F]florbetapir ([F]AV-45) has also been prepared by our new method.

Continuous flow photocyclization of stilbenes-scalable synthesis of functionalized phenanthrenes and helicenes

A continuous flow oxidative photocyclization of stilbene derivatives has been developed which allows the scalable synthesis of backbone functionalized phenanthrenes and helicenes of various sizes in good yields.

Synthesis of aryl(difluoromethylenephosphonates) via electrophilic fluorination of α-carbanions of benzylic phosphonates with N- fluorobenzenesulfonimide.

The electrophilic fluorination of a wide variety of benzylic phosphonates with N-fluorobenzenesulfonimide has been examined. The fluorination reaction proceeds well in the presence of an array of functional groups such as nitro, bromo, ketone, ester, phenyl and ether groups. Phenyl and biphenyl derivatives containing two α,α-difluoromethylenephosphonate groups can also be prepared. This procedure is compatible with methyl or ethyl phosphonate esters but not with t-butyl esters or with benzylic phosphonates containing an additional benzylic moiety at the para-position.