94209-48-0

Basic information

• Product Name: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[1,1'-biphenyl]-4-yl-5-ethyl-
• CAS NO: 94209-48-0
• Molecular Formula: C18H16N2O3
• Molecular Weight: 308.337
• Mol File: 94209-48-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[1,1'-biphenyl]-4-yl-5-ethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[1,1'-biphenyl]-4-yl-5-ethyl-(94209-48-0)
• EPA Substance Registry System: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[1,1'-biphenyl]-4-yl-5-ethyl-(94209-48-0)

Safety Data

• Hazardous Substances Data: 94209-48-0(Hazardous Substances Data)

Upstream product

• 57-13-6 urea 
• 349148-13-6 2-biphenyl-4-yl-2-ethyl-malonic acid dimethyl ester 
• 156140-46-4 dimethyl (4-biphenyl)malonate 
• 59793-29-2 methyl 2-(1,1'-biphenyl-4-yl)acetate 

Relevant articles and documents

Novel 5,5-disubstitutedpyrimidine-2,4,6-triones as selective MMP inhibitors

The 5,5-disubstitutedpyrimidine-2,4,6-triones represent a new class of MMP inhibitors showing selectivity for the gelatinases A and B, collagenase-3, and human neutrophil collagenase. The SAR presented here is in good agreement with an X-ray structure of compound 5 bound to the catalytic domain of stromelysin-1. While of the barbiturate structural class, compound 5 did not show any toxic or sedative effects.